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Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer.
Andradas C, Blasco-Benito S, Castillo-Lluva S, Dillenburg-Pilla P, Diez-Alarcia R, Juanes-García A, García-Taboada E, Hernando-Llorente R, Soriano J, Hamann S, Wenners A, Alkatout I, Klapper W, Rocken C, Bauer M, Arnold N, Quintanilla M, Megías D, Vicente-Manzanares M, Urigüen L, Gutkind JS, Guzmán M, Pérez-Gómez E, Sánchez C. Andradas C, et al. Among authors: gutkind js. Oncotarget. 2016 Jul 26;7(30):47565-47575. doi: 10.18632/oncotarget.10206. Oncotarget. 2016. PMID: 27340777 Free PMC article.
A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.
Vaqué JP, Dorsam RT, Feng X, Iglesias-Bartolome R, Forsthoefel DJ, Chen Q, Debant A, Seeger MA, Ksander BR, Teramoto H, Gutkind JS. Vaqué JP, et al. Among authors: gutkind js. Mol Cell. 2013 Jan 10;49(1):94-108. doi: 10.1016/j.molcel.2012.10.018. Epub 2012 Nov 21. Mol Cell. 2013. PMID: 23177739 Free PMC article.
SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis.
Dillenburg-Pilla P, Patel V, Mikelis CM, Zárate-Bladés CR, Doçi CL, Amornphimoltham P, Wang Z, Martin D, Leelahavanichkul K, Dorsam RT, Masedunskas A, Weigert R, Molinolo AA, Gutkind JS. Dillenburg-Pilla P, et al. Among authors: gutkind js. FASEB J. 2015 Mar;29(3):1056-68. doi: 10.1096/fj.14-260083. Epub 2014 Dec 2. FASEB J. 2015. PMID: 25466898 Free PMC article.
Oncotargeting G proteins: The Hippo in the room.
Feng X, Chen Q, Gutkind JS. Feng X, et al. Among authors: gutkind js. Oncotarget. 2014 Nov 30;5(22):10997-9. doi: 10.18632/oncotarget.2815. Oncotarget. 2014. PMID: 25526026 Free PMC article.
544 results