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Towards authentic transgenic mouse models of heritable PrP prion diseases.
Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. Watts JC, et al. Among authors: lee j. Acta Neuropathol. 2016 Oct;132(4):593-610. doi: 10.1007/s00401-016-1585-6. Epub 2016 Jun 28. Acta Neuropathol. 2016. PMID: 27350609 Free PMC article.
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients.
Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Watts JC, et al. Among authors: lee j. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10323-8. doi: 10.1073/pnas.1408900111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982139 Free PMC article.
Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain.
Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, DeGrado WF, Prusiner SB. Aoyagi A, et al. Among authors: lee jc. Sci Transl Med. 2019 May 1;11(490):eaat8462. doi: 10.1126/scitranslmed.aat8462. Sci Transl Med. 2019. PMID: 31043574 Free PMC article.
Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.
Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. Grandjean JM, et al. Among authors: lee j. ACS Med Chem Lett. 2020 Jan 30;11(2):127-132. doi: 10.1021/acsmedchemlett.9b00480. eCollection 2020 Feb 13. ACS Med Chem Lett. 2020. PMID: 32071678 Free PMC article.
Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease.
Casso-Chapa B, Vazquez González NA, Le NT, Palaskas NL, Nead KT, Eutsey LP, Samanthapudi VSK, Osborn AM, Lee J, Mejia G, Hoang O, Lin SH, Deswal A, Herrmann J, Wang G, Kirkland JL, Krishnan S, Wehrens XHT, Chini EN, Yusuf SW, Iliescu CA, Jain A, Burks JK, Seeley E, Lorenzi PL, Chau KM, Ostos Mendoza KC, Grumbach IM, Brookes PS, Hanssen NMJ, de Winther MPJ, Yvan-Charvet L, Kotla S, Schadler K, Abe JI. Casso-Chapa B, et al. Among authors: lee j. Arterioscler Thromb Vasc Biol. 2025 Jan 16. doi: 10.1161/ATVBAHA.124.319870. Online ahead of print. Arterioscler Thromb Vasc Biol. 2025. PMID: 39817327 Review.
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