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Page 1
Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.
Natoli TA, Smith LA, Rogers KA, Wang B, Komarnitsky S, Budman Y, Belenky A, Bukanov NO, Dackowski WR, Husson H, Russo RJ, Shayman JA, Ledbetter SR, Leonard JP, Ibraghimov-Beskrovnaya O. Natoli TA, et al. Among authors: ledbetter sr. Nat Med. 2010 Jul;16(7):788-92. doi: 10.1038/nm.2171. Epub 2010 Jun 20. Nat Med. 2010. PMID: 20562878 Free PMC article.
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease.
Natoli TA, Husson H, Rogers KA, Smith LA, Wang B, Budman Y, Bukanov NO, Ledbetter SR, Klinger KW, Leonard JP, Ibraghimov-Beskrovnaya O. Natoli TA, et al. Among authors: ledbetter sr. Hum Mol Genet. 2012 Aug 1;21(15):3397-407. doi: 10.1093/hmg/dds172. Epub 2012 May 4. Hum Mol Genet. 2012. PMID: 22563011 Free PMC article.
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Husson H, Moreno S, Smith LA, Smith MM, Russo RJ, Pitstick R, Sergeev M, Ledbetter SR, Bukanov NO, Lane M, Zhang K, Billot K, Carlson G, Shah J, Meijer L, Beier DR, Ibraghimov-Beskrovnaya O. Husson H, et al. Among authors: ledbetter sr. Hum Mol Genet. 2016 Jun 1;25(11):2245-2255. doi: 10.1093/hmg/ddw093. Epub 2016 Apr 5. Hum Mol Genet. 2016. PMID: 27053712 Free PMC article.
CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis.
Bracken C, Beauverger P, Duclos O, Russo RJ, Rogers KA, Husson H, Natoli TA, Ledbetter SR, Janiak P, Ibraghimov-Beskrovnaya O, Bukanov NO. Bracken C, et al. Among authors: ledbetter sr. Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1414-22. doi: 10.1152/ajprenal.00426.2015. Epub 2016 Apr 13. Am J Physiol Renal Physiol. 2016. PMID: 27076647 Free article.
Role of TGF-β in a mouse model of high turnover renal osteodystrophy.
Liu S, Song W, Boulanger JH, Tang W, Sabbagh Y, Kelley B, Gotschall R, Ryan S, Phillips L, Malley K, Cao X, Xia TH, Zhen G, Cao X, Ling H, Dechow PC, Bellido TM, Ledbetter SR, Schiavi SC. Liu S, et al. Among authors: ledbetter sr. J Bone Miner Res. 2014;29(5):1141-57. doi: 10.1002/jbmr.2120. J Bone Miner Res. 2014. PMID: 24166835 Free PMC article.
64 results