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BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells.
Schemionek M, Elling C, Steidl U, Bäumer N, Hamilton A, Spieker T, Göthert JR, Stehling M, Wagers A, Huettner CS, Tenen DG, Tickenbrock L, Berdel WE, Serve H, Holyoake TL, Müller-Tidow C, Koschmieder S. Schemionek M, et al. Among authors: gothert jr. Blood. 2010 Apr 22;115(16):3185-95. doi: 10.1182/blood-2009-04-215376. Epub 2010 Jan 6. Blood. 2010. PMID: 20053753 Free PMC article.
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Sprüssel A, Schulte JH, Weber S, Necke M, Händschke K, Thor T, Pajtler KW, Schramm A, König K, Diehl L, Mestdagh P, Vandesompele J, Speleman F, Jastrow H, Heukamp LC, Schüle R, Dührsen U, Buettner R, Eggert A, Göthert JR. Sprüssel A, et al. Among authors: gothert jr. Leukemia. 2012 Sep;26(9):2039-51. doi: 10.1038/leu.2012.157. Epub 2012 Jun 13. Leukemia. 2012. PMID: 22699452
Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML.
Solovey M, Wang Y, Michel C, Metzeler KH, Herold T, Göthert JR, Ellenrieder V, Hessmann E, Gattenlöhner S, Neubauer A, Pavlinic D, Benes V, Rupp O, Burchert A. Solovey M, et al. Among authors: gothert jr. J Hematol Oncol. 2019 Jul 8;12(1):72. doi: 10.1186/s13045-019-0765-y. J Hematol Oncol. 2019. PMID: 31286998 Free PMC article.
The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.
Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR. Göttgens B, et al. Among authors: gothert jr. Mol Cell Biol. 2004 Mar;24(5):1870-83. doi: 10.1128/MCB.24.5.1870-1883.2004. Mol Cell Biol. 2004. PMID: 14966269 Free PMC article.
55 results