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MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma.
Bell JB, Eckerdt FD, Alley K, Magnusson LP, Hussain H, Bi Y, Arslan AD, Clymer J, Alvarez AA, Goldman S, Cheng SY, Nakano I, Horbinski C, Davuluri RV, James CD, Platanias LC. Bell JB, et al. Among authors: alvarez aa. Mol Cancer Res. 2016 Oct;14(10):984-993. doi: 10.1158/1541-7786.MCR-16-0172. Epub 2016 Jun 30. Mol Cancer Res. 2016. PMID: 27364770 Free PMC article.
Noncoding RNAs in cancer and cancer stem cells.
Huang T, Alvarez A, Hu B, Cheng SY. Huang T, et al. Chin J Cancer. 2013 Nov;32(11):582-93. doi: 10.5732/cjc.013.10170. Chin J Cancer. 2013. PMID: 24206916 Free PMC article. Review.
A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.
Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. Huang T, et al. Among authors: alvarez aa. Nat Commun. 2016 Oct 4;7:12885. doi: 10.1038/ncomms12885. Nat Commun. 2016. PMID: 27698350 Free PMC article.
MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.
Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY. Huang T, et al. Among authors: alvarez aa. Cancer Cell. 2017 Dec 11;32(6):840-855.e8. doi: 10.1016/j.ccell.2017.11.005. Cancer Cell. 2017. PMID: 29232556 Free PMC article.
TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.
Sang Y, Li Y, Song L, Alvarez AA, Zhang W, Lv D, Tang J, Liu F, Chang Z, Hatakeyama S, Hu B, Cheng SY, Feng H. Sang Y, et al. Among authors: alvarez aa. Cancer Res. 2018 Apr 1;78(7):1792-1804. doi: 10.1158/0008-5472.CAN-17-2774. Epub 2018 Jan 31. Cancer Res. 2018. PMID: 29386185 Free PMC article.
Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma.
Pangeni RP, Zhang Z, Alvarez AA, Wan X, Sastry N, Lu S, Shi T, Huang T, Lei CX, James CD, Kessler JA, Brennan CW, Nakano I, Lu X, Hu B, Zhang W, Cheng SY. Pangeni RP, et al. Among authors: alvarez aa. Epigenetics. 2018;13(4):432-448. doi: 10.1080/15592294.2018.1469892. Epub 2018 Aug 6. Epigenetics. 2018. PMID: 29927689 Free PMC article.
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