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Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors.
LaPorte MG, Wang Z, Colombo R, Garzan A, Peshkov VA, Liang M, Johnston PA, Schurdak ME, Sen M, Camarco DP, Hua Y, Pollock NI, Lazo JS, Grandis JR, Wipf P, Huryn DM. LaPorte MG, et al. Among authors: huryn dm. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3581-5. doi: 10.1016/j.bmcl.2016.06.017. Epub 2016 Jun 9. Bioorg Med Chem Lett. 2016. PMID: 27381083 Free PMC article.
Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists.
Huryn DM, Ashwell S, Baudy R, Dressen DB, Gallaway W, Grant FS, Konradi A, Ley RW, Petusky S, Pleiss MA, Sarantakis D, Semko CM, Sherman MM, Tio C, Zhang L. Huryn DM, et al. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1651-4. doi: 10.1016/j.bmcl.2004.01.062. Bioorg Med Chem Lett. 2004. PMID: 15026043
Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: the confounding effects of DTT and cysteine in biological assays.
Myers MC, Napper AD, Motlekar N, Shah PP, Chiu CH, Beavers MP, Diamond SL, Huryn DM, Smith AB 3rd. Myers MC, et al. Among authors: huryn dm. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4761-6. doi: 10.1016/j.bmcl.2007.06.091. Epub 2007 Jul 5. Bioorg Med Chem Lett. 2007. PMID: 17656088 Free PMC article.
91 results