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Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer.
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Silliman N, Tacey M, Wong HL, Christie M, Kosmider S, Skinner I, Wong R, Steel M, Tran B, Desai J, Jones I, Haydon A, Hayes T, Price TJ, Strausberg RL, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P. Tie J, et al. Among authors: hayes t. Sci Transl Med. 2016 Jul 6;8(346):346ra92. doi: 10.1126/scitranslmed.aaf6219. Sci Transl Med. 2016. PMID: 27384348 Free PMC article.
Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer.
Tie J, Cohen JD, Lahouel K, Lo SN, Wang Y, Kosmider S, Wong R, Shapiro J, Lee M, Harris S, Khattak A, Burge M, Harris M, Lynam J, Nott L, Day F, Hayes T, McLachlan SA, Lee B, Ptak J, Silliman N, Dobbyn L, Popoli M, Hruban R, Lennon AM, Papadopoulos N, Kinzler KW, Vogelstein B, Tomasetti C, Gibbs P; DYNAMIC Investigators. Tie J, et al. Among authors: hayes t. N Engl J Med. 2022 Jun 16;386(24):2261-2272. doi: 10.1056/NEJMoa2200075. Epub 2022 Jun 4. N Engl J Med. 2022. PMID: 35657320 Free PMC article. Clinical Trial.
Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): an international, multicentre, phase 3, randomised, double-blind, placebo-controlled trial.
Chia JWK, Segelov E, Deng Y, Ho GF, Wang W, Han S, Sharma A, Ding K, Chen G, Jeffery MG, Tham CK, Ahn JB, Nott L, Zielinski R, Chao TY, van Hagen T, Wei PL, Day F, Mehta S, Yau T, Peng J, Hayes TM, Li Y, Gandhi M, Foo EMJ, Rahman N, Rothwell P, Ali R, Simes J, Toh HC. Chia JWK, et al. Among authors: hayes tm. Lancet Gastroenterol Hepatol. 2025 Jan 14:S2468-1253(24)00387-X. doi: 10.1016/S2468-1253(24)00387-X. Online ahead of print. Lancet Gastroenterol Hepatol. 2025. PMID: 39824200
Simulating 500 million years of evolution with a language model.
Hayes T, Rao R, Akin H, Sofroniew NJ, Oktay D, Lin Z, Verkuil R, Tran VQ, Deaton J, Wiggert M, Badkundri R, Shafkat I, Gong J, Derry A, Molina RS, Thomas N, Khan YA, Mishra C, Kim C, Bartie LJ, Nemeth M, Hsu PD, Sercu T, Candido S, Rives A. Hayes T, et al. Science. 2025 Jan 16:eads0018. doi: 10.1126/science.ads0018. Online ahead of print. Science. 2025. PMID: 39818825
828 results