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Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.
De Leo MG, Staiano L, Vicinanza M, Luciani A, Carissimo A, Mutarelli M, Di Campli A, Polishchuk E, Di Tullio G, Morra V, Levtchenko E, Oltrabella F, Starborg T, Santoro M, Di Bernardo D, Devuyst O, Lowe M, Medina DL, Ballabio A, De Matteis MA. De Leo MG, et al. Among authors: levtchenko e. Nat Cell Biol. 2016 Aug;18(8):839-850. doi: 10.1038/ncb3386. Epub 2016 Jul 11. Nat Cell Biol. 2016. PMID: 27398910 Free PMC article.
Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E. Elmonem MA, et al. Among authors: levtchenko e. Sci Rep. 2017 Feb 15;7:42583. doi: 10.1038/srep42583. Sci Rep. 2017. PMID: 28198397 Free PMC article.
Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis.
De Leo E, Elmonem MA, Berlingerio SP, Berquez M, Festa BP, Raso R, Bellomo F, Starborg T, Janssen MJ, Abbaszadeh Z, Cairoli S, Goffredo BM, Masereeuw R, Devuyst O, Lowe M, Levtchenko E, Luciani A, Emma F, Rega LR. De Leo E, et al. Among authors: levtchenko e. J Am Soc Nephrol. 2020 Jul;31(7):1522-1537. doi: 10.1681/ASN.2019090956. Epub 2020 Jun 5. J Am Soc Nephrol. 2020. PMID: 32503896 Free PMC article.
Studying nonobstructive azoospermia in cystinosis: histologic examination of testes and epididymis and sperm analysis in a Ctns⁻/⁻ mouse model.
Besouw MT, van Pelt AM, Gaide Chevronnay HP, Courtoy PJ, Pastore A, Goossens E, Devuyst O, Antignac C, Levtchenko EN. Besouw MT, et al. Among authors: levtchenko en. Fertil Steril. 2012 Jul;98(1):162-5. doi: 10.1016/j.fertnstert.2012.03.050. Epub 2012 May 10. Fertil Steril. 2012. PMID: 22578532 Free article.
Clinical utility gene card for: Lowe syndrome.
Bökenkamp A, Levtchenko E, Recker F, Ludwig M. Bökenkamp A, et al. Among authors: levtchenko e. Eur J Hum Genet. 2015 Jun;23(6):889-. doi: 10.1038/ejhg.2014.177. Epub 2014 Sep 3. Eur J Hum Genet. 2015. PMID: 25182134 Free PMC article. No abstract available.
An international cohort study spanning five decades assessed outcomes of nephropathic cystinosis.
Emma F, Hoff WV, Hohenfellner K, Topaloglu R, Greco M, Ariceta G, Bettini C, Bockenhauer D, Veys K, Pape L, Hulton S, Collin S, Ozaltin F, Servais A, Deschênes G, Novo R, Bertholet-Thomas A, Oh J, Cornelissen E, Janssen M, Haffner D, Ravà L, Antignac C, Devuyst O, Niaudet P, Levtchenko E. Emma F, et al. Among authors: levtchenko e. Kidney Int. 2021 Nov;100(5):1112-1123. doi: 10.1016/j.kint.2021.06.019. Epub 2021 Jul 6. Kidney Int. 2021. PMID: 34237326
301 results