Engelberg D - Search Results

1

Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation.

Goshen-Lago T, Goldberg-Carp A, Melamed D, Darlyuk-Saadon I, Bai C, Ahn NG, Admon A, Engelberg D. Goshen-Lago T, et al. Among authors: engelberg d. Mol Biol Cell. 2016 Sep 1;27(17):2771-83. doi: 10.1091/mbc.E16-03-0167. Epub 2016 Jul 13. Mol Biol Cell. 2016. PMID: 27413009 Free PMC article.

2

The yeast ras/cyclic AMP pathway induces invasive growth by suppressing the cellular stress response.

Stanhill A, Schick N, Engelberg D. Stanhill A, et al. Among authors: engelberg d. Mol Cell Biol. 1999 Nov;19(11):7529-38. doi: 10.1128/MCB.19.11.7529. Mol Cell Biol. 1999. PMID: 10523641 Free PMC article.

3

Isolation of hyperactive mutants of the MAPK p38/Hog1 that are independent of MAPK kinase activation.

Bell M, Capone R, Pashtan I, Levitzki A, Engelberg D. Bell M, et al. Among authors: engelberg d. J Biol Chem. 2001 Jul 6;276(27):25351-8. doi: 10.1074/jbc.M101818200. Epub 2001 Apr 17. J Biol Chem. 2001. PMID: 11309396 Free article.

4

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress.

Benhar M, Dalyot I, Engelberg D, Levitzki A. Benhar M, et al. Among authors: engelberg d. Mol Cell Biol. 2001 Oct;21(20):6913-26. doi: 10.1128/MCB.21.20.6913-6926.2001. Mol Cell Biol. 2001. PMID: 11564875 Free PMC article.

5

Phosphorylation of Tyr-176 of the yeast MAPK Hog1/p38 is not vital for Hog1 biological activity.

Bell M, Engelberg D. Bell M, et al. Among authors: engelberg d. J Biol Chem. 2003 Apr 25;278(17):14603-6. doi: 10.1074/jbc.C300006200. Epub 2003 Mar 10. J Biol Chem. 2003. PMID: 12637550 Free article.

6

Combination of two activating mutations in one HOG1 gene forms hyperactive enzymes that induce growth arrest.

Yaakov G, Bell M, Hohmann S, Engelberg D. Yaakov G, et al. Among authors: engelberg d. Mol Cell Biol. 2003 Jul;23(14):4826-40. doi: 10.1128/MCB.23.14.4826-4840.2003. Mol Cell Biol. 2003. PMID: 12832470 Free PMC article.

7

MAP-quest: could we produce constitutively active variants of MAP kinases?

Askari N, Diskin R, Avitzour M, Yaakov G, Livnah O, Engelberg D. Askari N, et al. Among authors: engelberg d. Mol Cell Endocrinol. 2006 Jun 27;252(1-2):231-40. doi: 10.1016/j.mce.2006.03.015. Epub 2006 May 2. Mol Cell Endocrinol. 2006. PMID: 16672172 Review.

8

Isolation of intrinsically active mutants of MAP kinases via genetic screens in yeast.

Engelberg D, Livnah O. Engelberg D, et al. Methods. 2006 Nov;40(3):255-61. doi: 10.1016/j.ymeth.2006.06.014. Methods. 2006. PMID: 16938468

9

Structures of p38alpha active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation.

Diskin R, Lebendiker M, Engelberg D, Livnah O. Diskin R, et al. Among authors: engelberg d. J Mol Biol. 2007 Jan 5;365(1):66-76. doi: 10.1016/j.jmb.2006.08.043. Epub 2006 Aug 22. J Mol Biol. 2007. PMID: 17059827

10

A novel lipid binding site formed by the MAP kinase insert in p38 alpha.

Diskin R, Engelberg D, Livnah O. Diskin R, et al. Among authors: engelberg d. J Mol Biol. 2008 Jan 4;375(1):70-9. doi: 10.1016/j.jmb.2007.09.002. Epub 2007 Sep 8. J Mol Biol. 2008. PMID: 17999933

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