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Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target.
Soares da Costa TP, Desbois S, Dogovski C, Gorman MA, Ketaren NE, Paxman JJ, Siddiqui T, Zammit LM, Abbott BM, Robins-Browne RM, Parker MW, Jameson GB, Hall NE, Panjikar S, Perugini MA. Soares da Costa TP, et al. Among authors: paxman jj. Structure. 2016 Aug 2;24(8):1282-1291. doi: 10.1016/j.str.2016.05.019. Epub 2016 Jul 14. Structure. 2016. PMID: 27427481 Free article.
The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes.
Paxman JJ, Borg NA, Horne J, Thompson PE, Chin Y, Sharma P, Simpson JS, Wielens J, Piek S, Kahler CM, Sakellaris H, Pearce M, Bottomley SP, Rossjohn J, Scanlon MJ. Paxman JJ, et al. J Biol Chem. 2009 Jun 26;284(26):17835-45. doi: 10.1074/jbc.M109.011502. Epub 2009 Apr 22. J Biol Chem. 2009. PMID: 19389711 Free PMC article.
Autotransporter Adhesins in Escherichia coli Pathogenesis.
Vo JL, Martínez Ortiz GC, Subedi P, Keerthikumar S, Mathivanan S, Paxman JJ, Heras B. Vo JL, et al. Among authors: paxman jj. Proteomics. 2017 Dec;17(23-24). doi: 10.1002/pmic.201600431. Epub 2017 Oct 12. Proteomics. 2017. PMID: 28665015 Review.
Production, biophysical characterization and initial crystallization studies of the N- and C-terminal domains of DsbD, an essential enzyme in Neisseria meningitidis.
Smith RP, Whitten AE, Paxman JJ, Kahler CM, Scanlon MJ, Heras B. Smith RP, et al. Among authors: paxman jj. Acta Crystallogr F Struct Biol Commun. 2018 Jan 1;74(Pt 1):31-38. doi: 10.1107/S2053230X17017800. Epub 2018 Jan 1. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29372905 Free PMC article.
27 results