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Page 1
Unveiling the power of high-dimensional cytometry data with cyCONDOR.
Kröger C, Müller S, Leidner J, Kröber T, Warnat-Herresthal S, Spintge JB, Zajac T, Neubauer A, Frolov A, Carraro C; DELCODE Study Group; Jessen F, Puccio S, Aschenbrenner AC, Schultze JL, Pecht T, Beyer MD, Bonaguro L. Kröger C, et al. Among authors: beyer md. Nat Commun. 2024 Dec 19;15(1):10702. doi: 10.1038/s41467-024-55179-w. Nat Commun. 2024. PMID: 39702306 Free PMC article.
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.
Knoll R, Helbig ET, Dahm K, Bolaji O, Hamm F, Dietrich O, van Uelft M, Müller S, Bonaguro L, Schulte-Schrepping J, Petrov L, Krämer B, Kraut M, Stubbemann P, Thibeault C, Brumhard S, Theis H, Hack G, De Domenico E, Nattermann J, Becker M, Beyer MD, Hillus D, Georg P, Loers C, Tiedemann J, Tober-Lau P, Lippert L, Millet Pascual-Leone B, Tacke F, Rohde G, Suttorp N, Witzenrath M; CAPNETZ Study Group; Pa-COVID-19 Study Group; Saliba AE, Ulas T, Polansky JK, Sawitzki B, Sander LE, Schultze JL, Aschenbrenner AC, Kurth F. Knoll R, et al. Among authors: beyer md. Cell. 2024 Aug 8;187(16):4318-4335.e20. doi: 10.1016/j.cell.2024.06.014. Epub 2024 Jul 3. Cell. 2024. PMID: 38964327 Free article.
Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.
Graelmann FJ, Gondorf F, Majlesain Y, Niemann B, Klepac K, Gosejacob D, Gottschalk M, Mayer M, Iriady I, Hatzfeld P, Lindenberg SK, Wunderling K, Thiele C, Abdullah Z, He W, Hiller K, Händler K, Beyer MD, Ulas T, Pfeifer A, Esser C, Weighardt H, Förster I, Reverte-Salisa L. Graelmann FJ, et al. Among authors: beyer md. Mol Metab. 2024 Jul;85:101963. doi: 10.1016/j.molmet.2024.101963. Epub 2024 May 29. Mol Metab. 2024. PMID: 38821174 Free PMC article.
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation.
Theobald H, Bejarano DA, Katzmarski N, Haub J, Schulte-Schrepping J, Yu J, Bassler K, Ament AL, Osei-Sarpong C, Piattini F, Vornholz L, T'Jonck W, Györfi AH, Hayer H, Yu X, Sheoran S, Al Jawazneh A, Chakarov S, Haendler K, Brown GD, Williams DL, Bosurgi L, Distler JHW, Ginhoux F, Ruland J, Beyer MD, Greter M, Bain CC, Vazquez-Armendariz AI, Kopf M, Schultze JL, Schlitzer A. Theobald H, et al. Among authors: beyer md. Nat Immunol. 2024 Jun;25(6):994-1006. doi: 10.1038/s41590-024-01830-z. Epub 2024 Apr 26. Nat Immunol. 2024. PMID: 38671323 Free PMC article.
Identification of drug candidates targeting monocyte reprogramming in people living with HIV.
Knoll R, Bonaguro L, Dos Santos JC, Warnat-Herresthal S, Jacobs-Cleophas MCP, Blümel E, Reusch N, Horne A, Herbert M, Nuesch-Germano M, Otten T, van der Heijden WA, van de Wijer L, Shalek AK, Händler K, Becker M, Beyer MD, Netea MG, Joosten LAB, van der Ven AJAM, Schultze JL, Aschenbrenner AC. Knoll R, et al. Among authors: beyer md. Front Immunol. 2023 Nov 20;14:1275136. doi: 10.3389/fimmu.2023.1275136. eCollection 2023. Front Immunol. 2023. PMID: 38077315 Free PMC article.
Fighting Post-COVID and ME/CFS - development of curative therapies.
Scheibenbogen C, Bellmann-Strobl JT, Heindrich C, Wittke K, Stein E, Franke C, Prüss H, Preßler H, Machule ML, Audebert H, Finke C, Zimmermann HG, Sawitzki B, Meisel C, Toelle M, Krueger A, Aschenbrenner AC, Schultze JL, Beyer MD, Ralser M, Mülleder M, Sander LE, Konietschke F, Paul F, Stojanov S, Bruckert L, Hedderich DM, Knolle F, Riemekasten G, Vehreschild MJGT, Cornely OA, Behrends U, Burock S. Scheibenbogen C, et al. Among authors: beyer md. Front Med (Lausanne). 2023 Jun 15;10:1194754. doi: 10.3389/fmed.2023.1194754. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37396922 Free PMC article.