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A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study.
Castelo-Branco P, Leão R, Lipman T, Campbell B, Lee D, Price A, Zhang C, Heidari A, Stephens D, Boerno S, Coelho H, Gomes A, Domingos C, Apolonio JD, Schäfer G, Bristow RG, Schweiger MR, Hamilton R, Zlotta A, Figueiredo A, Klocker H, Sültmann H, Tabori U. Castelo-Branco P, et al. Among authors: sultmann h. Oncotarget. 2016 Sep 6;7(36):57726-57736. doi: 10.18632/oncotarget.10639. Oncotarget. 2016. PMID: 27437772 Free PMC article.
Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity.
Kerick M, Isau M, Timmermann B, Sültmann H, Herwig R, Krobitsch S, Schaefer G, Verdorfer I, Bartsch G, Klocker H, Lehrach H, Schweiger MR. Kerick M, et al. Among authors: sultmann h. BMC Med Genomics. 2011 Sep 29;4:68. doi: 10.1186/1755-8794-4-68. BMC Med Genomics. 2011. PMID: 21958464 Free PMC article.
TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.
Brase JC, Johannes M, Mannsperger H, Fälth M, Metzger J, Kacprzyk LA, Andrasiuk T, Gade S, Meister M, Sirma H, Sauter G, Simon R, Schlomm T, Beissbarth T, Korf U, Kuner R, Sültmann H. Brase JC, et al. Among authors: sultmann h. BMC Cancer. 2011 Dec 5;11:507. doi: 10.1186/1471-2407-11-507. BMC Cancer. 2011. PMID: 22142399 Free PMC article.
Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.
Börno ST, Fischer A, Kerick M, Fälth M, Laible M, Brase JC, Kuner R, Dahl A, Grimm C, Sayanjali B, Isau M, Röhr C, Wunderlich A, Timmermann B, Claus R, Plass C, Graefen M, Simon R, Demichelis F, Rubin MA, Sauter G, Schlomm T, Sültmann H, Lehrach H, Schweiger MR. Börno ST, et al. Among authors: sultmann h. Cancer Discov. 2012 Nov;2(11):1024-35. doi: 10.1158/2159-8290.CD-12-0041. Epub 2012 Aug 28. Cancer Discov. 2012. PMID: 22930729
Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y.
Massoner P, Kugler KG, Unterberger K, Kuner R, Mueller LA, Fälth M, Schäfer G, Seifarth C, Ecker S, Verdorfer I, Graber A, Sültmann H, Klocker H. Massoner P, et al. Among authors: sultmann h. PLoS One. 2013;8(2):e55207. doi: 10.1371/journal.pone.0055207. Epub 2013 Feb 4. PLoS One. 2013. PMID: 23390522 Free PMC article.
220 results