Frank EG - Search Results

1

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes.

Maul RW, MacCarthy T, Frank EG, Donigan KA, McLenigan MP, Yang W, Saribasak H, Huston DE, Lange SS, Woodgate R, Gearhart PJ. Maul RW, et al. Among authors: frank eg. J Exp Med. 2016 Aug 22;213(9):1675-83. doi: 10.1084/jem.20151227. Epub 2016 Jul 25. J Exp Med. 2016. PMID: 27455952 Free PMC article.

2

129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation.

McDonald JP, Frank EG, Plosky BS, Rogozin IB, Masutani C, Hanaoka F, Woodgate R, Gearhart PJ. McDonald JP, et al. Among authors: frank eg. J Exp Med. 2003 Aug 18;198(4):635-43. doi: 10.1084/jem.20030767. J Exp Med. 2003. PMID: 12925679 Free PMC article.

3

DNA polymerase ι: The long and the short of it!

Frank EG, McLenigan MP, McDonald JP, Huston D, Mead S, Woodgate R. Frank EG, et al. DNA Repair (Amst). 2017 Oct;58:47-51. doi: 10.1016/j.dnarep.2017.08.006. Epub 2017 Aug 19. DNA Repair (Amst). 2017. PMID: 28865289 Free PMC article.

4

Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese.

Frank EG, Woodgate R. Frank EG, et al. J Biol Chem. 2007 Aug 24;282(34):24689-96. doi: 10.1074/jbc.M702159200. Epub 2007 Jul 2. J Biol Chem. 2007. PMID: 17609217 Free article.

5

A strategy for the expression of recombinant proteins traditionally hard to purify.

Frank EG, McDonald JP, Karata K, Huston D, Woodgate R. Frank EG, et al. Anal Biochem. 2012 Oct 15;429(2):132-9. doi: 10.1016/j.ab.2012.07.016. Epub 2012 Jul 22. Anal Biochem. 2012. PMID: 22828411 Free PMC article.

6

Posttranslational Regulation of Human DNA Polymerase ι.

McIntyre J, McLenigan MP, Frank EG, Dai X, Yang W, Wang Y, Woodgate R. McIntyre J, et al. Among authors: frank eg. J Biol Chem. 2015 Nov 6;290(45):27332-27344. doi: 10.1074/jbc.M115.675769. Epub 2015 Sep 14. J Biol Chem. 2015. PMID: 26370087 Free PMC article.

7

Mouse DNA polymerase ι lacking the forty-two amino acids encoded by exon-2 is catalytically inactive in vitro.

Frank EG, McDonald JP, Yang W, Woodgate R. Frank EG, et al. DNA Repair (Amst). 2017 Feb;50:71-76. doi: 10.1016/j.dnarep.2016.12.004. Epub 2016 Dec 21. DNA Repair (Amst). 2017. PMID: 28077247 Free PMC article.

8

Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template.

Frank EG, Tissier A, McDonald JP, Rapić-Otrin V, Zeng X, Gearhart PJ, Woodgate R. Frank EG, et al. EMBO J. 2001 Jun 1;20(11):2914-22. doi: 10.1093/emboj/20.11.2914. EMBO J. 2001. PMID: 11387224 Free PMC article.

9

poliota, a remarkably error-prone human DNA polymerase.

Tissier A, McDonald JP, Frank EG, Woodgate R. Tissier A, et al. Among authors: frank eg. Genes Dev. 2000 Jul 1;14(13):1642-50. Genes Dev. 2000. PMID: 10887158 Free PMC article.

10

Biochemical characterization of human DNA polymerase iota provides clues to its biological function.

Tissier A, Frank EG, McDonald JP, Vaisman A, Fernàndez de Henestrosa AR, Boudsocq F, McLenigan MP, Woodgate R. Tissier A, et al. Among authors: frank eg. Biochem Soc Trans. 2001 May;29(Pt 2):183-7. doi: 10.1042/0300-5127:0290183. Biochem Soc Trans. 2001. PMID: 11356150 Review.

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