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Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.
Elomaa O, Majuri I, Suomela S, Asumalahti K, Jiao H, Mirzaei Z, Rozell B, Dahlman-Wright K, Pispa J, Kere J, Saarialho-Kere U. Elomaa O, et al. Among authors: jiao h. Hum Mol Genet. 2004 Aug 1;13(15):1551-61. doi: 10.1093/hmg/ddh178. Epub 2004 Jun 9. Hum Mol Genet. 2004. PMID: 15190014
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.
Tiala I, Suomela S, Huuhtanen J, Wakkinen J, Hölttä-Vuori M, Kainu K, Ranta S, Turpeinen U, Hämäläinen E, Jiao H, Karvonen SL, Ikonen E, Kere J, Saarialho-Kere U, Elomaa O. Tiala I, et al. Among authors: jiao h. J Mol Med (Berl). 2007 Jun;85(6):589-601. doi: 10.1007/s00109-006-0155-0. Epub 2007 Jan 13. J Mol Med (Berl). 2007. PMID: 17221218
Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells.
Otonkoski T, Jiao H, Kaminen-Ahola N, Tapia-Paez I, Ullah MS, Parton LE, Schuit F, Quintens R, Sipilä I, Mayatepek E, Meissner T, Halestrap AP, Rutter GA, Kere J. Otonkoski T, et al. Among authors: jiao h. Am J Hum Genet. 2007 Sep;81(3):467-74. doi: 10.1086/520960. Epub 2007 Jul 26. Am J Hum Genet. 2007. PMID: 17701893 Free PMC article.
1,655 results