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Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, Saal LH. She QB, et al. Among authors: lau yk. BMC Cancer. 2016 Aug 2;16:587. doi: 10.1186/s12885-016-2609-2. BMC Cancer. 2016. PMID: 27484095 Free PMC article.
Metformin and erlotinib synergize to inhibit basal breast cancer.
Lau YK, Du X, Rayannavar V, Hopkins B, Shaw J, Bessler E, Thomas T, Pires MM, Keniry M, Parsons RE, Cremers S, Szabolcs M, Maurer MA. Lau YK, et al. Oncotarget. 2014 Nov 15;5(21):10503-17. doi: 10.18632/oncotarget.2391. Oncotarget. 2014. PMID: 25361177 Free PMC article.
Survival factor NFIL3 restricts FOXO-induced gene expression in cancer.
Keniry M, Pires MM, Mense S, Lefebvre C, Gan B, Justiano K, Lau YK, Hopkins B, Hodakoski C, Koujak S, Toole J, Fenton F, Calahan A, Califano A, DePinho RA, Maurer M, Parsons R. Keniry M, et al. Among authors: lau yk. Genes Dev. 2013 Apr 15;27(8):916-27. doi: 10.1101/gad.214049.113. Genes Dev. 2013. PMID: 23630076 Free PMC article.
Merlin is a potent inhibitor of glioma growth.
Lau YK, Murray LB, Houshmandi SS, Xu Y, Gutmann DH, Yu Q. Lau YK, et al. Cancer Res. 2008 Jul 15;68(14):5733-42. doi: 10.1158/0008-5472.CAN-08-0190. Cancer Res. 2008. PMID: 18632626 Free PMC article.
Merlin is a negative regulator of human melanoma growth.
Murray LB, Lau YK, Yu Q. Murray LB, et al. Among authors: lau yk. PLoS One. 2012;7(8):e43295. doi: 10.1371/journal.pone.0043295. Epub 2012 Aug 17. PLoS One. 2012. PMID: 22912849 Free PMC article.
The tobacco quitline setting as a teachable moment: The Educating Quitline Users About Lung (EQUAL) cancer screening randomized trial.
Webster M, Whealan J, Williams RM, Eyestone E, Le A, Childs J, Kao JY, Martin M, Wolfe S, Yang F, Hung PY, Lau YK, Luta G, Tammemagi M, Meza R, Taylor KL. Webster M, et al. Among authors: lau yk. Transl Behav Med. 2023 Sep 28;13(10):736-747. doi: 10.1093/tbm/ibad049. Transl Behav Med. 2023. PMID: 37616531 Clinical Trial.
176 results