Parsons R - Search Results

1

Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.

She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, Saal LH. She QB, et al. Among authors: parsons r. BMC Cancer. 2016 Aug 2;16:587. doi: 10.1186/s12885-016-2609-2. BMC Cancer. 2016. PMID: 27484095 Free PMC article.

2

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.

Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. Li J, et al. Among authors: parsons r. Science. 1997 Mar 28;275(5308):1943-7. doi: 10.1126/science.275.5308.1943. Science. 1997. PMID: 9072974

3

Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas.

Bose S, Wang SI, Terry MB, Hibshoosh H, Parsons R. Bose S, et al. Among authors: parsons r. Oncogene. 1998 Jul 9;17(1):123-7. doi: 10.1038/sj.onc.1201940. Oncogene. 1998. PMID: 9671321

4

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.

Li J, Simpson L, Takahashi M, Miliaresis C, Myers MP, Tonks N, Parsons R. Li J, et al. Among authors: parsons r. Cancer Res. 1998 Dec 15;58(24):5667-72. Cancer Res. 1998. PMID: 9865719

5

Reduced expression of PTEN correlates with breast cancer progression.

Bose S, Crane A, Hibshoosh H, Mansukhani M, Sandweis L, Parsons R. Bose S, et al. Among authors: parsons r. Hum Pathol. 2002 Apr;33(4):405-9. doi: 10.1053/hupa.2002.124721. Hum Pathol. 2002. PMID: 12055674

6

PTEN and cancer.

Parsons R, Simpson L. Parsons R, et al. Methods Mol Biol. 2003;222:147-66. doi: 10.1385/1-59259-328-3:147. Methods Mol Biol. 2003. PMID: 12710685 Review. No abstract available.

7

Human cancer, PTEN and the PI-3 kinase pathway.

Parsons R. Parsons R. Semin Cell Dev Biol. 2004 Apr;15(2):171-6. doi: 10.1016/j.semcdb.2003.12.021. Semin Cell Dev Biol. 2004. PMID: 15209376 Review.

8

Lack of PTEN sequesters CHK1 and initiates genetic instability.

Puc J, Keniry M, Li HS, Pandita TK, Choudhury AD, Memeo L, Mansukhani M, Murty VV, Gaciong Z, Meek SE, Piwnica-Worms H, Hibshoosh H, Parsons R. Puc J, et al. Among authors: parsons r. Cancer Cell. 2005 Feb;7(2):193-204. doi: 10.1016/j.ccr.2005.01.009. Cancer Cell. 2005. PMID: 15710331 Free article.

9

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma.

Saal LH, Holm K, Maurer M, Memeo L, Su T, Wang X, Yu JS, Malmström PO, Mansukhani M, Enoksson J, Hibshoosh H, Borg A, Parsons R. Saal LH, et al. Among authors: parsons r. Cancer Res. 2005 Apr 1;65(7):2554-9. doi: 10.1158/0008-5472-CAN-04-3913. Cancer Res. 2005. PMID: 15805248

10

HIN-1, an inhibitor of cell growth, invasion, and AKT activation.

Krop I, Parker MT, Bloushtain-Qimron N, Porter D, Gelman R, Sasaki H, Maurer M, Terry MB, Parsons R, Polyak K. Krop I, et al. Among authors: parsons r. Cancer Res. 2005 Nov 1;65(21):9659-69. doi: 10.1158/0008-5472.CAN-05-1663. Cancer Res. 2005. PMID: 16266985

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