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Fungus-Derived Neoechinulin B as a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System.
Nakajima S, Watashi K, Ohashi H, Kamisuki S, Izaguirre-Carbonell J, Kwon AT, Suzuki H, Kataoka M, Tsukuda S, Okada M, Moi ML, Takeuchi T, Arita M, Suzuki R, Aizaki H, Kato T, Suzuki T, Hasegawa H, Takasaki T, Sugawara F, Wakita T. Nakajima S, et al. Among authors: takeuchi t. J Virol. 2016 Sep 29;90(20):9058-74. doi: 10.1128/JVI.00856-16. Print 2016 Oct 15. J Virol. 2016. PMID: 27489280 Free PMC article.
Total synthesis and anti-hepatitis C virus activity of MA026.
Shimura S, Ishima M, Nakajima S, Fujii T, Himeno N, Ikeda K, Izaguirre-Carbonell J, Murata H, Takeuchi T, Kamisuki S, Suzuki T, Kuramochi K, Watashi K, Kobayashi S, Sugawara F. Shimura S, et al. Among authors: takeuchi t. J Am Chem Soc. 2013 Dec 18;135(50):18949-56. doi: 10.1021/ja410145x. Epub 2013 Dec 6. J Am Chem Soc. 2013. PMID: 24251365
Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication.
Kamata M, Takeuchi T, Hayashi E, Nishioka K, Oshima M, Iwamoto M, Nishiuchi K, Kamo S, Tomoshige S, Watashi K, Kamisuki S, Ohrui H, Sugawara F, Kuramochi K. Kamata M, et al. Among authors: takeuchi t. Biosci Biotechnol Biochem. 2020 Feb;84(2):217-227. doi: 10.1080/09168451.2019.1673696. Epub 2019 Oct 7. Biosci Biotechnol Biochem. 2020. PMID: 31589093
Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.
Izaguirre-Carbonell J, Kawakubo H, Murata H, Tanabe A, Takeuchi T, Kusayanagi T, Tsukuda S, Hirakawa T, Iwabata K, Kanai Y, Ohta K, Miura M, Sakaguchi K, Matsunaga S, Sahara H, Kamisuki S, Sugawara F. Izaguirre-Carbonell J, et al. Among authors: takeuchi t. Sci Rep. 2015 Oct 12;5:15136. doi: 10.1038/srep15136. Sci Rep. 2015. PMID: 26456697 Free PMC article.
The antitumor agent doxorubicin binds to Fanconi anemia group F protein.
Kusayanagi T, Tsukuda S, Shimura S, Manita D, Iwakiri K, Kamisuki S, Takakusagi Y, Takeuchi T, Kuramochi K, Nakazaki A, Sakaguchi K, Kobayashi S, Sugawara F. Kusayanagi T, et al. Among authors: takeuchi t. Bioorg Med Chem. 2012 Nov 1;20(21):6248-55. doi: 10.1016/j.bmc.2012.09.015. Epub 2012 Sep 16. Bioorg Med Chem. 2012. PMID: 23026082
5,715 results