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Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.
Miyanaga A, Janso JE, McDonald L, He M, Liu H, Barbieri L, Eustáquio AS, Fielding EN, Carter GT, Jensen PR, Feng X, Leighton M, Koehn FE, Moore BS. Miyanaga A, et al. Among authors: fielding en. J Am Chem Soc. 2011 Aug 31;133(34):13311-3. doi: 10.1021/ja205655w. Epub 2011 Aug 9. J Am Chem Soc. 2011. PMID: 21815669 Free PMC article.
Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Chen PY, Adak S, Chekan JR, Liscombe DK, Miyanaga A, Bernhardt P, Diethelm S, Fielding EN, George JH, Miles ZD, Murray LAM, Steele TS, Winter JM, Noel JP, Moore BS. Chen PY, et al. Among authors: fielding en. Biochemistry. 2022 Sep 6;61(17):1844-1852. doi: 10.1021/acs.biochem.2c00338. Epub 2022 Aug 19. Biochemistry. 2022. PMID: 35985031 Free PMC article.
Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC.
Fielding EN, Widboom PF, Bruner SD. Fielding EN, et al. Biochemistry. 2007 Dec 11;46(49):13994-4000. doi: 10.1021/bi701148b. Epub 2007 Nov 16. Biochemistry. 2007. PMID: 18004875
The X-ray structure of DpgC [Widboom, P. W., Fielding, E. N., Liu, Y., and Bruner, S. D. (2007) Nature 447, 342-345] confirmed the absence of cofactors and defined a novel hydrophobic dioxygen binding pocket adjacent to a bound substrate analogue. ...
The X-ray structure of DpgC [Widboom, P. W., Fielding, E. N., Liu, Y., and Bruner, S. D. (2007) Nature 447, 342-345] confirmed …
Home- vs Office-Based Narrowband UV-B Phototherapy for Patients With Psoriasis: The LITE Randomized Clinical Trial.
Gelfand JM, Armstrong AW, Lim HW, Feldman SR, Johnson SM, Claiborne WCC, Kalb RE, Jakus J, Mangold AR, Flowers RH, Bhutani T, Durkin JR, Bagel J, Fretzin S, Sheehan MP, Krell J, Reeder M, Kaffenberger J, Kartono F, Takeshita J, Bridges AM, Fielding E, Nehal US, Schaecher KL, Howard LM, Eakin GS, Báez S, Bishop BE, Fitzsimmons RC Jr, Papadopoulos M, Song WB, Linn KA, Hubbard RA, Shin DB, Callis Duffin K. Gelfand JM, et al. Among authors: fielding e. JAMA Dermatol. 2024 Dec 1;160(12):1320-1328. doi: 10.1001/jamadermatol.2024.3897. JAMA Dermatol. 2024. PMID: 39319513 Clinical Trial.
62 results