Kraytsberg Y - Search Results

1

Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis.

Safdar A, Annis S, Kraytsberg Y, Laverack C, Saleem A, Popadin K, Woods DC, Tilly JL, Khrapko K. Safdar A, et al. Among authors: kraytsberg y. Curr Opin Genet Dev. 2016 Jun;38:127-132. doi: 10.1016/j.gde.2016.06.011. Epub 2016 Aug 3. Curr Opin Genet Dev. 2016. PMID: 27497229 Free PMC article. Review.

2

Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?

Khrapko K, Kraytsberg Y, de Grey AD, Vijg J, Schon EA. Khrapko K, et al. Among authors: kraytsberg y. Aging Cell. 2006 Jun;5(3):279-82. doi: 10.1111/j.1474-9726.2006.00209.x. Aging Cell. 2006. PMID: 16842501 Free article.

3

Do mtDNA deletions drive premature aging in mtDNA mutator mice?

Kraytsberg Y, Simon DK, Turnbull DM, Khrapko K. Kraytsberg Y, et al. Aging Cell. 2009 Aug;8(4):502-6. doi: 10.1111/j.1474-9726.2009.00484.x. Epub 2009 Apr 22. Aging Cell. 2009. PMID: 19416127 Free PMC article.

4

mtLOH (mitochondrial loss of heteroplasmy), aging, and 'surrogate self'.

Nekhaeva E, Kraytsberg Y, Khrapko K. Nekhaeva E, et al. Among authors: kraytsberg y. Mech Ageing Dev. 2002 Apr 30;123(8):891-8. doi: 10.1016/s0047-6374(02)00026-x. Mech Ageing Dev. 2002. PMID: 12044937 Review.

5

Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process?

Kraytsberg Y, Nekhaeva E, Bodyak NB, Khrapko K. Kraytsberg Y, et al. Mech Ageing Dev. 2003 Jan;124(1):49-53. doi: 10.1016/s0047-6374(02)00169-0. Mech Ageing Dev. 2003. PMID: 12618006 Review.

6

Where and when do somatic mtDNA mutations occur?

Khrapko K, Ebralidse K, Kraytsberg Y. Khrapko K, et al. Among authors: kraytsberg y. Ann N Y Acad Sci. 2004 Jun;1019:240-4. doi: 10.1196/annals.1297.040. Ann N Y Acad Sci. 2004. PMID: 15247022 Review.

7

On the timing and the extent of clonal expansion of mtDNA deletions: evidence from single-molecule PCR.

Nicholas A, Kraytsberg Y, Guo X, Khrapko K. Nicholas A, et al. Among authors: kraytsberg y. Exp Neurol. 2009 Aug;218(2):316-9. doi: 10.1016/j.expneurol.2009.04.029. Epub 2009 May 6. Exp Neurol. 2009. PMID: 19426731 Free PMC article.

8

Mitochondrial DNA deletions in mice in men: substantia nigra is much less affected in the mouse.

Guo X, Kudryavtseva E, Bodyak N, Nicholas A, Dombrovsky I, Yang D, Kraytsberg Y, Simon DK, Khrapko K. Guo X, et al. Among authors: kraytsberg y. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1159-62. doi: 10.1016/j.bbabio.2010.04.005. Epub 2010 Apr 11. Biochim Biophys Acta. 2010. PMID: 20388490 Free PMC article.

9

Repeats, longevity and the sources of mtDNA deletions: evidence from 'deletional spectra'.

Guo X, Popadin KY, Markuzon N, Orlov YL, Kraytsberg Y, Krishnan KJ, Zsurka G, Turnbull DM, Kunz WS, Khrapko K. Guo X, et al. Among authors: kraytsberg y. Trends Genet. 2010 Aug;26(8):340-3. doi: 10.1016/j.tig.2010.05.006. Epub 2010 Jun 28. Trends Genet. 2010. PMID: 20591530 Free PMC article.

10

When man got his mtDNA deletions?

Popadin K, Safdar A, Kraytsberg Y, Khrapko K. Popadin K, et al. Among authors: kraytsberg y. Aging Cell. 2014 Aug;13(4):579-82. doi: 10.1111/acel.12231. Epub 2014 Jun 4. Aging Cell. 2014. PMID: 24894296 Free PMC article.

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