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Page 1
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.
Zhou K, Yee SW, Seiser EL, van Leeuwen N, Tavendale R, Bennett AJ, Groves CJ, Coleman RL, van der Heijden AA, Beulens JW, de Keyser CE, Zaharenko L, Rotroff DM, Out M, Jablonski KA, Chen L, Javorský M, Židzik J, Levin AM, Williams LK, Dujic T, Semiz S, Kubo M, Chien HC, Maeda S, Witte JS, Wu L, Tkáč I, Kooy A, van Schaik RHN, Stehouwer CDA, Logie L; MetGen Investigators; DPP Investigators; ACCORD Investigators; Sutherland C, Klovins J, Pirags V, Hofman A, Stricker BH, Motsinger-Reif AA, Wagner MJ, Innocenti F, 't Hart LM, Holman RR, McCarthy MI, Hedderson MM, Palmer CNA, Florez JC, Giacomini KM, Pearson ER. Zhou K, et al. Among authors: zidzik j. Nat Genet. 2016 Sep;48(9):1055-1059. doi: 10.1038/ng.3632. Epub 2016 Aug 8. Nat Genet. 2016. PMID: 27500523 Free PMC article.
Variation in KCNQ1 is associated with therapeutic response to sulphonylureas.
Schroner Z, Dobrikova M, Klimcakova L, Javorsky M, Zidzik J, Kozarova M, Hudakova T, Tkacova R, Salagovic J, Tkac I. Schroner Z, et al. Among authors: zidzik j. Med Sci Monit. 2011 Jul;17(7):CR392-6. doi: 10.12659/msm.881850. Med Sci Monit. 2011. PMID: 21709633 Free PMC article.
KCNJ11 gene E23K variant and therapeutic response to sulfonylureas.
Javorsky M, Klimcakova L, Schroner Z, Zidzik J, Babjakova E, Fabianova M, Kozarova M, Tkacova R, Salagovic J, Tkac I. Javorsky M, et al. Among authors: zidzik j. Eur J Intern Med. 2012 Apr;23(3):245-9. doi: 10.1016/j.ejim.2011.10.018. Epub 2011 Nov 26. Eur J Intern Med. 2012. PMID: 22385882 Clinical Trial.
A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes.
Tkáč I, Javorský M, Klimčáková L, Židzik J, Gaľa I, Babjaková E, Schroner Z, Štolfová M, Hermanová H, Habalová V. Tkáč I, et al. Among authors: zidzik j. Eur J Clin Pharmacol. 2015 Jan;71(1):59-63. doi: 10.1007/s00228-014-1774-y. Epub 2014 Oct 21. Eur J Clin Pharmacol. 2015. PMID: 25327507 Clinical Trial.
Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.
Zaharenko L, Kalnina I, Geldnere K, Konrade I, Grinberga S, Židzik J, Javorský M, Lejnieks A, Nikitina-Zake L, Fridmanis D, Peculis R, Radovica-Spalvina I, Hartmane D, Pugovics O, Tkáč I, Klimčáková L, Pīrāgs V, Klovins J. Zaharenko L, et al. Among authors: zidzik j. Eur J Endocrinol. 2016 Dec;175(6):531-540. doi: 10.1530/EJE-16-0347. Epub 2016 Sep 8. Eur J Endocrinol. 2016. PMID: 27609360
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