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Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL-31 neutralizing antibody.
Lewis KE, Holdren MS, Maurer MF, Underwood S, Meengs B, Julien SH, Byrnes-Blake KA, Freeman JA, Bukowski TR, Wolf AC, Hamacher NB, Rixon MW, Dillon SR. Lewis KE, et al. Among authors: byrnes blake ka. J Eur Acad Dermatol Venereol. 2017 Jan;31(1):142-150. doi: 10.1111/jdv.13794. Epub 2016 Aug 8. J Eur Acad Dermatol Venereol. 2017. PMID: 27501029
Engineering of stable bispecific antibodies targeting IL-17A and IL-23.
Mabry R, Lewis KE, Moore M, McKernan PA, Bukowski TR, Bontadelli K, Brender T, Okada S, Lum K, West J, Kuijper JL, Ardourel D, Franke S, Lockwood L, Vu T, Frank A, Appleby MW, Wolf A, Reardon B, Hamacher NB, Stevens B, Lewis P, Lewis KB, Gilbertson DG, Lantry M, Julien SH, Ostrander C, Chan C, Byrnes-Blake K, Brody J, Presnell S, Meengs B, Levin SD, Snavely M. Mabry R, et al. Protein Eng Des Sel. 2010 Mar;23(3):115-27. doi: 10.1093/protein/gzp073. Epub 2009 Dec 18. Protein Eng Des Sel. 2010. PMID: 20022918
Nonclinical Profile of BLZ-100, a Tumor-Targeting Fluorescent Imaging Agent.
Parrish-Novak J, Byrnes-Blake K, Lalayeva N, Burleson S, Fidel J, Gilmore R, Gayheart-Walsten P, Bricker GA, Crumb WJ Jr, Tarlo KS, Hansen S, Wiss V, Malta E, Dernell WS, Olson JM, Miller DM. Parrish-Novak J, et al. Int J Toxicol. 2017 Mar/Apr;36(2):104-112. doi: 10.1177/1091581817697685. Epub 2017 Mar 17. Int J Toxicol. 2017. PMID: 28403743 Free PMC article.
20 results