Sacchettini JC - Search Results

1

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase.

Palencia A, Li X, Bu W, Choi W, Ding CZ, Easom EE, Feng L, Hernandez V, Houston P, Liu L, Meewan M, Mohan M, Rock FL, Sexton H, Zhang S, Zhou Y, Wan B, Wang Y, Franzblau SG, Woolhiser L, Gruppo V, Lenaerts AJ, O'Malley T, Parish T, Cooper CB, Waters MG, Ma Z, Ioerger TR, Sacchettini JC, Rullas J, Angulo-Barturen I, Pérez-Herrán E, Mendoza A, Barros D, Cusack S, Plattner JJ, Alley MR. Palencia A, et al. Among authors: sacchettini jc. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6271-80. doi: 10.1128/AAC.01339-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27503647 Free PMC article.

2

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis.

Rozwarski DA, Grant GA, Barton DH, Jacobs WR Jr, Sacchettini JC. Rozwarski DA, et al. Among authors: sacchettini jc. Science. 1998 Jan 2;279(5347):98-102. doi: 10.1126/science.279.5347.98. Science. 1998. PMID: 9417034

3

TEXTAL: a pattern recognition system for interpreting electron density maps.

Ioerger TR, Holton T, Christopher JA, Sacchettini JC. Ioerger TR, et al. Among authors: sacchettini jc. Proc Int Conf Intell Syst Mol Biol. 1999:130-7. Proc Int Conf Intell Syst Mol Biol. 1999. PMID: 10786295

4

Determining protein structure from electron-density maps using pattern matching.

Holton T, Ioerger TR, Christopher JA, Sacchettini JC. Holton T, et al. Among authors: sacchettini jc. Acta Crystallogr D Biol Crystallogr. 2000 Jun;56(Pt 6):722-34. doi: 10.1107/s0907444900003450. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10818349

5

Automatic modeling of protein backbones in electron-density maps via prediction of Calpha coordinates.

Ioerger TR, Sacchettini JC. Ioerger TR, et al. Among authors: sacchettini jc. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2043-54. doi: 10.1107/s0907444902016724. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454463

6

TB drug discovery: addressing issues of persistence and resistance.

Smith CV, Sharma V, Sacchettini JC. Smith CV, et al. Among authors: sacchettini jc. Tuberculosis (Edinb). 2004;84(1-2):45-55. doi: 10.1016/j.tube.2003.08.019. Tuberculosis (Edinb). 2004. PMID: 14670345 Review.

7

Mycobacterium tuberculosis: a model system for structural genomics.

Smith CV, Sacchettini JC. Smith CV, et al. Among authors: sacchettini jc. Curr Opin Struct Biol. 2003 Dec;13(6):658-64. doi: 10.1016/j.sbi.2003.10.004. Curr Opin Struct Biol. 2003. PMID: 14675542 Review.

8

TEXTAL system: artificial intelligence techniques for automated protein model building.

Ioerger TR, Sacchettini JC. Ioerger TR, et al. Among authors: sacchettini jc. Methods Enzymol. 2003;374:244-70. doi: 10.1016/S0076-6879(03)74012-9. Methods Enzymol. 2003. PMID: 14696377 No abstract available.

9

Determining relevant features to recognize electron density patterns in x-ray protein crystallography.

Gopal K, Romo TD, Sacchettini JC, Ioerger TR. Gopal K, et al. Among authors: sacchettini jc. J Bioinform Comput Biol. 2005 Jun;3(3):645-76. doi: 10.1142/s0219720005001272. J Bioinform Comput Biol. 2005. PMID: 16108088

10

FINDMOL: automated identification of macromolecules in electron-density maps.

McKee EW, Kanbi LD, Childs KL, Grosse-Kunstleve RW, Adams PD, Sacchettini JC, Ioerger TR. McKee EW, et al. Among authors: sacchettini jc. Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1514-20. doi: 10.1107/S0907444905027332. Epub 2005 Oct 19. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 16239729

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