Zhang X - Search Results

1

Beyond knockout: A novel homodimerization-targeting MyD88 inhibitor prevents and cures type 1 diabetes in NOD mice.

Zhang X, Xing S, Li M, Zhang L, Xie L, He W, Liu J, Chang S, Jiang F, Zhou P. Zhang X, et al. Among authors: zhang l. Metabolism. 2016 Sep;65(9):1267-77. doi: 10.1016/j.metabol.2016.05.005. Epub 2016 May 14. Metabolism. 2016. PMID: 27506734

2

The MyD88 inhibitor TJ-M2010-2 suppresses proliferation, migration and invasion of breast cancer cells by regulating MyD88/GSK-3β and MyD88/NF-κB signalling pathways.

Liu JH, Chen C, Li ZY, Zou ZM, Gao DC, Zhang X, Kuang XW, Sun ZH, Zheng WJ, Zhou P, Sun SR. Liu JH, et al. Among authors: zhang x. Exp Cell Res. 2020 Sep 15;394(2):112157. doi: 10.1016/j.yexcr.2020.112157. Epub 2020 Jun 29. Exp Cell Res. 2020. PMID: 32610185

3

Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer.

Xie L, Jiang FC, Zhang LM, He WT, Liu JH, Li MQ, Zhang X, Xing S, Guo H, Zhou P. Xie L, et al. Among authors: zhang x, zhang lm. J Natl Cancer Inst. 2015 Dec 28;108(4):djv364. doi: 10.1093/jnci/djv364. Print 2016 Apr. J Natl Cancer Inst. 2015. PMID: 26712311

4

Pharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro.

Zhang LM, Liu JH, Xue CB, Li MQ, Xing S, Zhang X, He WT, Jiang FC, Lu X, Zhou P. Zhang LM, et al. Among authors: zhang x. Sci Rep. 2016 Jun 1;6:26954. doi: 10.1038/srep26954. Sci Rep. 2016. PMID: 27246399 Free PMC article.

5

Short-term Pharmacological Inhibition of MyD88 Homodimerization by a Novel Inhibitor Promotes Robust Allograft Tolerance in Mouse Cardiac and Skin Transplantation.

Li C, Zhang LM, Zhang X, Huang X, Liu Y, Li MQ, Xing S, Yang T, Xie L, Jiang FC, Jiang HY, He WT, Zhou P. Li C, et al. Among authors: zhang x, zhang lm. Transplantation. 2017 Feb;101(2):284-293. doi: 10.1097/TP.0000000000001471. Transplantation. 2017. PMID: 27607533

6

A Novel Inhibitor of Homodimerization Targeting MyD88 Ameliorates Renal Interstitial Fibrosis by Counteracting TGF-β1-Induced EMT in Vivo and in Vitro.

Liu JH, He L, Zou ZM, Ding ZC, Zhang X, Wang H, Zhou P, Xie L, Xing S, Yi CZ. Liu JH, et al. Among authors: zhang x. Kidney Blood Press Res. 2018;43(5):1677-1687. doi: 10.1159/000494745. Epub 2018 Oct 31. Kidney Blood Press Res. 2018. PMID: 30380557 Free article.

7

A novel MyD88 inhibitor attenuates allograft rejection after heterotopic tracheal transplantation in mice.

Yang M, Chen G, Zhang X, Ding Z, Miao Y, Yang Y, Chen ZK, Jiang F, Chang S, Zhou P. Yang M, et al. Among authors: zhang x. Transpl Immunol. 2019 Apr;53:1-6. doi: 10.1016/j.trim.2018.11.006. Epub 2018 Nov 22. Transpl Immunol. 2019. PMID: 30472390

8

Modulating the conformation of the TIR domain by a neoteric MyD88 inhibitor leads to the separation of GVHD from GVT.

Xing S, Zhang X, Huang X, Xie L, Jiang F, Zhou P. Xing S, et al. Among authors: zhang x. Leuk Lymphoma. 2019 Jun;60(6):1528-1539. doi: 10.1080/10428194.2018.1537487. Epub 2018 Dec 3. Leuk Lymphoma. 2019. PMID: 30501537

9

Short-term use of MyD88 inhibitor TJ-M2010-5 prevents d-galactosamine/lipopolysaccharide-induced acute liver injury in mice.

Ding Z, Du D, Yang Y, Yang M, Miao Y, Zou Z, Zhang X, Li Z, Zhang X, Zhang L, Wang X, Zhao Y, Jiang J, Jiang F, Zhou P. Ding Z, et al. Among authors: zhang l, zhang x. Int Immunopharmacol. 2019 Feb;67:356-365. doi: 10.1016/j.intimp.2018.11.051. Epub 2018 Dec 21. Int Immunopharmacol. 2019. PMID: 30583234

10

Implication of myeloid differentiation factor 88 inhibitor TJ-M2010-5 for therapeutic intervention of hepatocellular carcinoma.

Liu J, Zhang X, Wang H, Zhang M, Peng Y, Li M, Xie L, Jiang F, Gong Y, Zhao Q, Zhou P. Liu J, et al. Among authors: zhang m, zhang x. Hepatol Res. 2019 Oct;49(10):1182-1194. doi: 10.1111/hepr.13359. Epub 2019 May 9. Hepatol Res. 2019. PMID: 31074165

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