Kahn J - Search Results

1

Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.

Leyton-Jaimes MF, Benaim C, Abu-Hamad S, Kahn J, Guetta A, Bucala R, Israelson A. Leyton-Jaimes MF, et al. Among authors: kahn j. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10198-203. doi: 10.1073/pnas.1604600113. Epub 2016 Aug 22. Proc Natl Acad Sci U S A. 2016. PMID: 27551074 Free PMC article.

2

Macrophage migration inhibitory factor: A multifaceted cytokine implicated in multiple neurological diseases.

Leyton-Jaimes MF, Kahn J, Israelson A. Leyton-Jaimes MF, et al. Among authors: kahn j. Exp Neurol. 2018 Mar;301(Pt B):83-91. doi: 10.1016/j.expneurol.2017.06.021. Epub 2017 Jul 2. Exp Neurol. 2018. PMID: 28679106 Review.

3

Misfolded SOD1 Accumulation and Mitochondrial Association Contribute to the Selective Vulnerability of Motor Neurons in Familial ALS: Correlation to Human Disease.

Abu-Hamad S, Kahn J, Leyton-Jaimes MF, Rosenblatt J, Israelson A. Abu-Hamad S, et al. Among authors: kahn j. ACS Chem Neurosci. 2017 Oct 18;8(10):2225-2234. doi: 10.1021/acschemneuro.7b00140. Epub 2017 Jul 31. ACS Chem Neurosci. 2017. PMID: 28715630

4

MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS.

Shvil N, Banerjee V, Zoltsman G, Shani T, Kahn J, Abu-Hamad S, Papo N, Engel S, Bernhagen J, Israelson A. Shvil N, et al. Among authors: kahn j. Cell Death Dis. 2018 Jan 25;9(2):107. doi: 10.1038/s41419-017-0130-4. Cell Death Dis. 2018. PMID: 29371591 Free PMC article.

5

Synapsins regulate α-synuclein functions.

Atias M, Tevet Y, Sun J, Stavsky A, Tal S, Kahn J, Roy S, Gitler D. Atias M, et al. Among authors: kahn j. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11116-11118. doi: 10.1073/pnas.1903054116. Epub 2019 May 20. Proc Natl Acad Sci U S A. 2019. PMID: 31110014 Free PMC article.

6

AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS.

Leyton-Jaimes MF, Kahn J, Israelson A. Leyton-Jaimes MF, et al. Among authors: kahn j. Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14755-14760. doi: 10.1073/pnas.1904665116. Epub 2019 Jul 1. Proc Natl Acad Sci U S A. 2019. PMID: 31262807 Free PMC article.

7

All Roads Lead to Rome: Different Molecular Players Converge to Common Toxic Pathways in Neurodegeneration.

Argueti-Ostrovsky S, Alfahel L, Kahn J, Israelson A. Argueti-Ostrovsky S, et al. Among authors: kahn j. Cells. 2021 Sep 16;10(9):2438. doi: 10.3390/cells10092438. Cells. 2021. PMID: 34572087 Free PMC article. Review.

8

MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1.

Alaskarov A, Barel S, Bakavayev S, Kahn J, Israelson A. Alaskarov A, et al. Among authors: kahn j. Sci Rep. 2022 Jun 10;12(1):9570. doi: 10.1038/s41598-022-13744-7. Sci Rep. 2022. PMID: 35688953 Free PMC article.

9

4-Phenylbutyric Acid (4-PBA) Derivatives Prevent SOD1 Amyloid Aggregation In Vitro with No Effect on Disease Progression in SOD1-ALS Mice.

Alfahel L, Argueti-Ostrovsky S, Barel S, Ali Saleh M, Kahn J, Azoulay-Ginsburg S, Rothstein A, Ebbinghaus S, Gruzman A, Israelson A. Alfahel L, et al. Among authors: kahn j. Int J Mol Sci. 2022 Aug 20;23(16):9403. doi: 10.3390/ijms23169403. Int J Mol Sci. 2022. PMID: 36012668 Free PMC article.

10

Targeting low levels of MIF expression as a potential therapeutic strategy for ALS.

Alfahel L, Gschwendtberger T, Kozareva V, Dumas L, Gibbs R, Kertser A, Baruch K, Zaccai S, Kahn J, Thau-Habermann N, Eggenschwiler R, Sterneckert J, Hermann A, Sundararaman N, Vaibhav V, Van Eyk JE, Rafuse VF, Fraenkel E, Cantz T, Petri S, Israelson A. Alfahel L, et al. Among authors: kahn j. Cell Rep Med. 2024 May 21;5(5):101546. doi: 10.1016/j.xcrm.2024.101546. Epub 2024 May 3. Cell Rep Med. 2024. PMID: 38703766 Free PMC article.

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