Wiederkum S - Search Results

1

Charge heterogeneity: Basic antibody charge variants with increased binding to Fc receptors.

Hintersteiner B, Lingg N, Zhang P, Woen S, Hoi KM, Stranner S, Wiederkum S, Mutschlechner O, Schuster M, Loibner H, Jungbauer A. Hintersteiner B, et al. Among authors: wiederkum s. MAbs. 2016 Nov/Dec;8(8):1548-1560. doi: 10.1080/19420862.2016.1225642. Epub 2016 Aug 25. MAbs. 2016. PMID: 27559765 Free PMC article.

2

Improved effector functions of a therapeutic monoclonal Lewis Y-specific antibody by glycoform engineering.

Schuster M, Umana P, Ferrara C, Brünker P, Gerdes C, Waxenecker G, Wiederkum S, Schwager C, Loibner H, Himmler G, Mudde GC. Schuster M, et al. Among authors: wiederkum s. Cancer Res. 2005 Sep 1;65(17):7934-41. doi: 10.1158/0008-5472.CAN-04-4212. Cancer Res. 2005. PMID: 16140965

3

In vivo glyco-engineered antibody with improved lytic potential produced by an innovative non-mammalian expression system.

Schuster M, Jost W, Mudde GC, Wiederkum S, Schwager C, Janzek E, Altmann F, Stadlmann J, Stemmer C, Gorr G. Schuster M, et al. Among authors: wiederkum s. Biotechnol J. 2007 Jun;2(6):700-8. doi: 10.1002/biot.200600255. Biotechnol J. 2007. PMID: 17427997

4

Compensation of endogenous IgG mediated inhibition of antibody-dependent cellular cytotoxicity by glyco-engineering of therapeutic antibodies.

Nechansky A, Schuster M, Jost W, Siegl P, Wiederkum S, Gorr G, Kircheis R. Nechansky A, et al. Among authors: wiederkum s. Mol Immunol. 2007 Mar;44(7):1815-7. doi: 10.1016/j.molimm.2006.08.013. Epub 2006 Oct 2. Mol Immunol. 2007. PMID: 17011625

5

Correlation between CD16a binding and immuno effector functionality of an antigen specific immunoglobulin Fc fragment (Fcab).

Kainer M, Antes B, Wiederkum S, Wozniak-Knopp G, Bauer A, Rüker F, Woisetschläger M. Kainer M, et al. Among authors: wiederkum s. Arch Biochem Biophys. 2012 Oct 15;526(2):154-8. doi: 10.1016/j.abb.2012.05.010. Epub 2012 May 23. Arch Biochem Biophys. 2012. PMID: 22634259

6

In vivo and in vitro activity of an immunoglobulin Fc fragment (Fcab) with engineered Her-2/neu binding sites.

Woisetschläger M, Antes B, Borrowdale R, Wiederkum S, Kainer M, Steinkellner H, Wozniak-Knopp G, Moulder K, Rüker F, Mudde GC. Woisetschläger M, et al. Among authors: wiederkum s. Biotechnol J. 2014 Jun;9(6):844-51. doi: 10.1002/biot.201300387. Epub 2014 May 8. Biotechnol J. 2014. PMID: 24806546

7

Significant impact of single N-glycan residues on the biological activity of Fc-based antibody-like fragments.

Jez J, Antes B, Castilho A, Kainer M, Wiederkum S, Grass J, Rüker F, Woisetschläger M, Steinkellner H. Jez J, et al. Among authors: wiederkum s. J Biol Chem. 2012 Jul 13;287(29):24313-9. doi: 10.1074/jbc.M112.360701. Epub 2012 May 15. J Biol Chem. 2012. PMID: 22589538 Free PMC article.

8

Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display.

Traxlmayr MW, Lobner E, Antes B, Kainer M, Wiederkum S, Hasenhindl C, Stadlmayr G, Rüker F, Woisetschläger M, Moulder K, Obinger C. Traxlmayr MW, et al. Among authors: wiederkum s. Protein Eng Des Sel. 2013 Apr;26(4):255-65. doi: 10.1093/protein/gzs102. Epub 2012 Dec 23. Protein Eng Des Sel. 2013. PMID: 23267121

9

Influence of carboxymethyl dextran and ferric citrate on the adhesion of CHO cells on microcarriers.

Landauer K, Wiederkum S, Dürrschmid M, Klug H, Simic G, Blüml G, Doblhoff-Dier O. Landauer K, et al. Among authors: wiederkum s. Biotechnol Prog. 2003 Jan-Feb;19(1):21-9. doi: 10.1021/bp025568l. Biotechnol Prog. 2003. PMID: 12573002

10

Detachment factors for enhanced carrier to carrier transfer of CHO cell lines on macroporous microcarriers.

Landauer K, Dürrschmid M, Klug H, Wiederkum S, Blüml G, Doblhoff-Dier O. Landauer K, et al. Among authors: wiederkum s. Cytotechnology. 2002 May;39(1):37-45. doi: 10.1023/A:1022455525323. Cytotechnology. 2002. PMID: 19003302 Free PMC article.

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