Lau P - Search Results

1

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control.

Tuong ZK, Fitzsimmons R, Wang SM, Oh TG, Lau P, Steyn F, Thomas G, Muscat GEO. Tuong ZK, et al. Among authors: lau p. EBioMedicine. 2016 Sep;11:101-117. doi: 10.1016/j.ebiom.2016.08.027. Epub 2016 Aug 20. EBioMedicine. 2016. PMID: 27568222 Free PMC article.

2

The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

Lau P, Fitzsimmons RL, Raichur S, Wang SC, Lechtken A, Muscat GE. Lau P, et al. J Biol Chem. 2008 Jun 27;283(26):18411-21. doi: 10.1074/jbc.M710526200. Epub 2008 Apr 25. J Biol Chem. 2008. PMID: 18441015 Free article.

3

Retinoid-related orphan receptor alpha and the regulation of lipid homeostasis.

Fitzsimmons RL, Lau P, Muscat GE. Fitzsimmons RL, et al. Among authors: lau p. J Steroid Biochem Mol Biol. 2012 Jul;130(3-5):159-68. doi: 10.1016/j.jsbmb.2011.06.009. Epub 2011 Jun 23. J Steroid Biochem Mol Biol. 2012. PMID: 21723946 Review.

4

Rorα deficiency and decreased adiposity are associated with induction of thermogenic gene expression in subcutaneous white adipose and brown adipose tissue.

Lau P, Tuong ZK, Wang SC, Fitzsimmons RL, Goode JM, Thomas GP, Cowin GJ, Pearen MA, Mardon K, Stow JL, Muscat GE. Lau P, et al. Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E159-71. doi: 10.1152/ajpendo.00056.2014. Epub 2014 Nov 25. Am J Physiol Endocrinol Metab. 2015. PMID: 25424999 Free article.

5

RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages.

Tuong ZK, Lau P, Du X, Condon ND, Goode JM, Oh TG, Yeo JC, Muscat GE, Stow JL. Tuong ZK, et al. Among authors: lau p. PLoS One. 2016 Jan 26;11(1):e0147179. doi: 10.1371/journal.pone.0147179. eCollection 2016. PLoS One. 2016. PMID: 26812621 Free PMC article.

6

Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle.

Raichur S, Fitzsimmons RL, Myers SA, Pearen MA, Lau P, Eriksson N, Wang SM, Muscat GE. Raichur S, et al. Among authors: lau p. Nucleic Acids Res. 2010 Jul;38(13):4296-312. doi: 10.1093/nar/gkq180. Epub 2010 Mar 24. Nucleic Acids Res. 2010. PMID: 20338882 Free PMC article.

7

Characterization of the retinoid orphan-related receptor-alpha coactivator binding interface: a structural basis for ligand-independent transcription.

Harris JM, Lau P, Chen SL, Muscat GE. Harris JM, et al. Among authors: lau p. Mol Endocrinol. 2002 May;16(5):998-1012. doi: 10.1210/mend.16.5.0837. Mol Endocrinol. 2002. PMID: 11981035

8

RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR.

Lau P, Nixon SJ, Parton RG, Muscat GE. Lau P, et al. J Biol Chem. 2004 Aug 27;279(35):36828-40. doi: 10.1074/jbc.M404927200. Epub 2004 Jun 15. J Biol Chem. 2004. PMID: 15199055 Free article.

9

Rev-erbbeta regulates the expression of genes involved in lipid absorption in skeletal muscle cells: evidence for cross-talk between orphan nuclear receptors and myokines.

Ramakrishnan SN, Lau P, Burke LJ, Muscat GE. Ramakrishnan SN, et al. Among authors: lau p. J Biol Chem. 2005 Mar 11;280(10):8651-9. doi: 10.1074/jbc.M413949200. Epub 2004 Dec 28. J Biol Chem. 2005. PMID: 15623503 Free article.

10

Raichur S, Lau P, Staels B, Muscat GE. Raichur S, et al. Among authors: lau p. J Mol Endocrinol. 2007 Jul;39(1):29-44. doi: 10.1677/jme.1.00010. J Mol Endocrinol. 2007. PMID: 17601883

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