Huang M - Search Results

1

A substrate-driven allosteric switch that enhances PDI catalytic activity.

Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. Bekendam RH, et al. Among authors: huang m. Nat Commun. 2016 Aug 30;7:12579. doi: 10.1038/ncomms12579. Nat Commun. 2016. PMID: 27573496 Free PMC article.

2

Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.

Huang M, Rigby AC, Morelli X, Grant MA, Huang G, Furie B, Seaton B, Furie BC. Huang M, et al. Among authors: huang g. Nat Struct Biol. 2003 Sep;10(9):751-6. doi: 10.1038/nsb971. Epub 2003 Aug 17. Nat Struct Biol. 2003. PMID: 12923575

3

Crystal structure of the calcium-stabilized human factor IX Gla domain bound to a conformation-specific anti-factor IX antibody.

Huang M, Furie BC, Furie B. Huang M, et al. J Biol Chem. 2004 Apr 2;279(14):14338-46. doi: 10.1074/jbc.M314011200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722079 Free article.

4

Structure of human urokinase plasminogen activator in complex with its receptor.

Huai Q, Mazar AP, Kuo A, Parry GC, Shaw DE, Callahan J, Li Y, Yuan C, Bian C, Chen L, Furie B, Furie BC, Cines DB, Huang M. Huai Q, et al. Among authors: huang m. Science. 2006 Feb 3;311(5761):656-9. doi: 10.1126/science.1121143. Science. 2006. PMID: 16456079

5

Crystal structure of the bovine lactadherin C2 domain, a membrane binding motif, shows similarity to the C2 domains of factor V and factor VIII.

Lin L, Huai Q, Huang M, Furie B, Furie BC. Lin L, et al. Among authors: huang m. J Mol Biol. 2007 Aug 17;371(3):717-24. doi: 10.1016/j.jmb.2007.05.054. Epub 2007 May 25. J Mol Biol. 2007. PMID: 17583728 Free PMC article.

6

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes.

Huai Q, Zhou A, Lin L, Mazar AP, Parry GC, Callahan J, Shaw DE, Furie B, Furie BC, Huang M. Huai Q, et al. Among authors: huang m. Nat Struct Mol Biol. 2008 Apr;15(4):422-3. doi: 10.1038/nsmb.1404. Epub 2008 Mar 23. Nat Struct Mol Biol. 2008. PMID: 18376415 Free PMC article.

7

Challenges for drug discovery - a case study of urokinase receptor inhibition.

Chen Z, Lin L, Huai Q, Huang M. Chen Z, et al. Among authors: huang m. Comb Chem High Throughput Screen. 2009 Dec;12(10):961-7. doi: 10.2174/138620709789824727. Comb Chem High Throughput Screen. 2009. PMID: 20025562 Free PMC article.

8

Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.

Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Liu Z, et al. Among authors: huang m. J Biol Chem. 2010 Mar 19;285(12):8824-9. doi: 10.1074/jbc.M109.080168. Epub 2010 Jan 20. J Biol Chem. 2010. PMID: 20089867 Free PMC article.

9

Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy.

Lin L, Gårdsvoll H, Huai Q, Huang M, Ploug M. Lin L, et al. Among authors: huang m. J Biol Chem. 2010 Apr 2;285(14):10982-92. doi: 10.1074/jbc.M109.093492. Epub 2010 Feb 4. J Biol Chem. 2010. PMID: 20133942 Free PMC article.

10

Crystal structure of the urokinase receptor in a ligand-free form.

Xu X, Gårdsvoll H, Yuan C, Lin L, Ploug M, Huang M. Xu X, et al. Among authors: huang m. J Mol Biol. 2012 Mar 9;416(5):629-41. doi: 10.1016/j.jmb.2011.12.058. Epub 2012 Jan 21. J Mol Biol. 2012. PMID: 22285761

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