Gerwick WH - Search Results

1

Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.

Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Maloney FP, et al. Among authors: gerwick l, gerwick wh. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10316-21. doi: 10.1073/pnas.1607210113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573844 Free PMC article.

2

The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit.

Chang Z, Flatt P, Gerwick WH, Nguyen VA, Willis CL, Sherman DH. Chang Z, et al. Among authors: gerwick wh. Gene. 2002 Aug 21;296(1-2):235-47. doi: 10.1016/s0378-1119(02)00860-0. Gene. 2002. PMID: 12383521

3

Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.

Chang Z, Sitachitta N, Rossi JV, Roberts MA, Flatt PM, Jia J, Sherman DH, Gerwick WH. Chang Z, et al. Among authors: gerwick wh. J Nat Prod. 2004 Aug;67(8):1356-67. doi: 10.1021/np0499261. J Nat Prod. 2004. PMID: 15332855

4

Characterization of the initial enzymatic steps of barbamide biosynthesis.

Flatt PM, O'Connell SJ, McPhail KL, Zeller G, Willis CL, Sherman DH, Gerwick WH. Flatt PM, et al. Among authors: gerwick wh. J Nat Prod. 2006 Jun;69(6):938-44. doi: 10.1021/np050523q. J Nat Prod. 2006. PMID: 16792414

5

Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair.

Gu L, Jia J, Liu H, Håkansson K, Gerwick WH, Sherman DH. Gu L, et al. Among authors: gerwick wh. J Am Chem Soc. 2006 Jul 19;128(28):9014-5. doi: 10.1021/ja0626382. J Am Chem Soc. 2006. PMID: 16834357

6

Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.

Geders TW, Gu L, Mowers JC, Liu H, Gerwick WH, Håkansson K, Sherman DH, Smith JL. Geders TW, et al. Among authors: gerwick wh. J Biol Chem. 2007 Dec 7;282(49):35954-63. doi: 10.1074/jbc.M703921200. Epub 2007 Oct 10. J Biol Chem. 2007. PMID: 17928301 Free article.

7

GNAT-like strategy for polyketide chain initiation.

Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. Gu L, et al. Among authors: gerwick wh. Science. 2007 Nov 9;318(5852):970-4. doi: 10.1126/science.1148790. Science. 2007. PMID: 17991863

8

Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis.

Simmons TL, Engene N, Ureña LD, Romero LI, Ortega-Barría E, Gerwick L, Gerwick WH. Simmons TL, et al. Among authors: gerwick l, gerwick wh. J Nat Prod. 2008 Sep;71(9):1544-50. doi: 10.1021/np800110e. Epub 2008 Aug 21. J Nat Prod. 2008. PMID: 18715036 Free PMC article.

9

New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria.

Jones AC, Gu L, Sorrels CM, Sherman DH, Gerwick WH. Jones AC, et al. Among authors: gerwick wh. Curr Opin Chem Biol. 2009 Apr;13(2):216-23. doi: 10.1016/j.cbpa.2009.02.019. Epub 2009 Mar 21. Curr Opin Chem Biol. 2009. PMID: 19307147 Free PMC article. Review.

10

Probing marine natural product defenses with DESI-imaging mass spectrometry.

Esquenazi E, Dorrestein PC, Gerwick WH. Esquenazi E, et al. Among authors: gerwick wh. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7269-70. doi: 10.1073/pnas.0902840106. Epub 2009 Apr 28. Proc Natl Acad Sci U S A. 2009. PMID: 19416917 Free PMC article. No abstract available.

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