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Circumventing the stability-function trade-off in an engineered FN3 domain.
Porebski BT, Conroy PJ, Drinkwater N, Schofield P, Vazquez-Lombardi R, Hunter MR, Hoke DE, Christ D, McGowan S, Buckle AM. Porebski BT, et al. Among authors: hoke de. Protein Eng Des Sel. 2016 Nov 1;29(11):541-550. doi: 10.1093/protein/gzw046. Protein Eng Des Sel. 2016. PMID: 27578887 Free PMC article.
Smoothing a rugged protein folding landscape by sequence-based redesign.
Porebski BT, Keleher S, Hollins JJ, Nickson AA, Marijanovic EM, Borg NA, Costa MG, Pearce MA, Dai W, Zhu L, Irving JA, Hoke DE, Kass I, Whisstock JC, Bottomley SP, Webb GI, McGowan S, Buckle AM. Porebski BT, et al. Among authors: hoke de. Sci Rep. 2016 Sep 26;6:33958. doi: 10.1038/srep33958. Sci Rep. 2016. PMID: 27667094 Free PMC article.
Reactive centre loop dynamics and serpin specificity.
Marijanovic EM, Fodor J, Riley BT, Porebski BT, Costa MGS, Kass I, Hoke DE, McGowan S, Buckle AM. Marijanovic EM, et al. Among authors: hoke de. Sci Rep. 2019 Mar 7;9(1):3870. doi: 10.1038/s41598-019-40432-w. Sci Rep. 2019. PMID: 30846766 Free PMC article.
Mutational and biophysical robustness in a prestabilized monobody.
Chandler PG, Tan LL, Porebski BT, Green JS, Riley BT, Broendum SS, Hoke DE, Falconer RJ, Munro TP, Buckle M, Jackson CJ, Buckle AM. Chandler PG, et al. Among authors: hoke de. J Biol Chem. 2021 Jan-Jun;296:100447. doi: 10.1016/j.jbc.2021.100447. Epub 2021 Feb 20. J Biol Chem. 2021. PMID: 33617878 Free PMC article.
37 results