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Page 1
Statins improve NASH via inhibition of RhoA and Ras.
Schierwagen R, Maybüchen L, Hittatiya K, Klein S, Uschner FE, Braga TT, Franklin BS, Nickenig G, Strassburg CP, Plat J, Sauerbruch T, Latz E, Lütjohann D, Zimmer S, Trebicka J. Schierwagen R, et al. Among authors: franklin bs. Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1;311(4):G724-G733. doi: 10.1152/ajpgi.00063.2016. Epub 2016 Sep 15. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27634010 Free article.
Endothelial microparticle uptake in target cells is annexin I/phosphatidylserine receptor dependent and prevents apoptosis.
Jansen F, Yang X, Hoyer FF, Paul K, Heiermann N, Becher MU, Abu Hussein N, Kebschull M, Bedorf J, Franklin BS, Latz E, Nickenig G, Werner N. Jansen F, et al. Among authors: franklin bs. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1925-35. doi: 10.1161/ATVBAHA.112.253229. Epub 2012 Jun 14. Arterioscler Thromb Vasc Biol. 2012. PMID: 22701020
Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles.
Jansen F, Yang X, Hoelscher M, Cattelan A, Schmitz T, Proebsting S, Wenzel D, Vosen S, Franklin BS, Fleischmann BK, Nickenig G, Werner N. Jansen F, et al. Among authors: franklin bs. Circulation. 2013 Oct 29;128(18):2026-38. doi: 10.1161/CIRCULATIONAHA.113.001720. Epub 2013 Sep 6. Circulation. 2013. PMID: 24014835
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
MicroRNA expression in circulating microvesicles predicts cardiovascular events in patients with coronary artery disease.
Jansen F, Yang X, Proebsting S, Hoelscher M, Przybilla D, Baumann K, Schmitz T, Dolf A, Endl E, Franklin BS, Sinning JM, Vasa-Nicotera M, Nickenig G, Werner N. Jansen F, et al. Among authors: franklin bs. J Am Heart Assoc. 2014 Oct 27;3(6):e001249. doi: 10.1161/JAHA.114.001249. J Am Heart Assoc. 2014. PMID: 25349183 Free PMC article.
Crystal Formation in Inflammation.
Franklin BS, Mangan MS, Latz E. Franklin BS, et al. Annu Rev Immunol. 2016 May 20;34:173-202. doi: 10.1146/annurev-immunol-041015-055539. Epub 2016 Jan 11. Annu Rev Immunol. 2016. PMID: 26772211 Review.
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