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Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation.
Rutkowski MR, Stephen TL, Svoronos N, Allegrezza MJ, Tesone AJ, Perales-Puchalt A, Brencicova E, Escovar-Fadul X, Nguyen JM, Cadungog MG, Zhang R, Salatino M, Tchou J, Rabinovich GA, Conejo-Garcia JR. Rutkowski MR, et al. Cancer Cell. 2015 Jan 12;27(1):27-40. doi: 10.1016/j.ccell.2014.11.009. Epub 2014 Dec 18. Cancer Cell. 2015. PMID: 25533336 Free PMC article.
Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.
Svoronos N, Perales-Puchalt A, Allegrezza MJ, Rutkowski MR, Payne KK, Tesone AJ, Nguyen JM, Curiel TJ, Cadungog MG, Singhal S, Eruslanov EB, Zhang P, Tchou J, Zhang R, Conejo-Garcia JR. Svoronos N, et al. Cancer Discov. 2017 Jan;7(1):72-85. doi: 10.1158/2159-8290.CD-16-0502. Epub 2016 Sep 30. Cancer Discov. 2017. PMID: 27694385 Free PMC article.
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R. Yokoyama Y, et al. Cancer Res. 2016 Nov 1;76(21):6320-6330. doi: 10.1158/0008-5472.CAN-16-0854. Cancer Res. 2016. PMID: 27803105 Free PMC article.
SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells.
Stephen TL, Payne KK, Chaurio RA, Allegrezza MJ, Zhu H, Perez-Sanz J, Perales-Puchalt A, Nguyen JM, Vara-Ailor AE, Eruslanov EB, Borowsky ME, Zhang R, Laufer TM, Conejo-Garcia JR. Stephen TL, et al. Immunity. 2017 Jan 17;46(1):51-64. doi: 10.1016/j.immuni.2016.12.015. Immunity. 2017. PMID: 28099864 Free PMC article.
ARID1A-mutated ovarian cancers depend on HDAC6 activity.
Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher FJ III, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, Christianson DW, Zhang R. Bitler BG, et al. Nat Cell Biol. 2017 Aug;19(8):962-973. doi: 10.1038/ncb3582. Epub 2017 Jul 24. Nat Cell Biol. 2017. PMID: 28737768 Free PMC article.
198 results