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mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function.
Paschoal VA, Amano MT, Belchior T, Magdalon J, Chimin P, Andrade ML, Ortiz-Silva M, Castro É, Yamashita AS, Rosa Neto JC, Câmara NO, Festuccia WT. Paschoal VA, et al. Among authors: festuccia wt. Immunobiology. 2017 Feb;222(2):261-271. doi: 10.1016/j.imbio.2016.09.014. Epub 2016 Sep 28. Immunobiology. 2017. PMID: 27692982
Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice.
Vinolo MA, Rodrigues HG, Festuccia WT, Crisma AR, Alves VS, Martins AR, Amaral CL, Fiamoncini J, Hirabara SM, Sato FT, Fock RA, Malheiros G, dos Santos MF, Curi R. Vinolo MA, et al. Among authors: festuccia wt. Am J Physiol Endocrinol Metab. 2012 Jul 15;303(2):E272-82. doi: 10.1152/ajpendo.00053.2012. Epub 2012 May 22. Am J Physiol Endocrinol Metab. 2012. PMID: 22621868 Free article.
Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner.
Bolsoni-Lopes A, Festuccia WT, Farias TS, Chimin P, Torres-Leal FL, Derogis PB, de Andrade PB, Miyamoto S, Lima FB, Curi R, Alonso-Vale MI. Bolsoni-Lopes A, et al. Among authors: festuccia wt. Am J Physiol Endocrinol Metab. 2013 Nov 1;305(9):E1093-102. doi: 10.1152/ajpendo.00082.2013. Epub 2013 Sep 10. Am J Physiol Endocrinol Metab. 2013. PMID: 24022867 Free article.
Omega-3 fatty acids protect from diet-induced obesity, glucose intolerance, and adipose tissue inflammation through PPARγ-dependent and PPARγ-independent actions.
Belchior T, Paschoal VA, Magdalon J, Chimin P, Farias TM, Chaves-Filho AB, Gorjão R, St-Pierre P, Miyamoto S, Kang JX, Deshaies Y, Marette A, Festuccia W. Belchior T, et al. Mol Nutr Food Res. 2015 May;59(5):957-67. doi: 10.1002/mnfr.201400914. Epub 2015 Mar 16. Mol Nutr Food Res. 2015. PMID: 25641959
Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.
Magdalon J, Chimin P, Belchior T, Neves RX, Vieira-Lara MA, Andrade ML, Farias TS, Bolsoni-Lopes A, Paschoal VA, Yamashita AS, Kowaltowski AJ, Festuccia WT. Magdalon J, et al. Among authors: festuccia wt. Biochim Biophys Acta. 2016 May;1861(5):430-8. doi: 10.1016/j.bbalip.2016.02.023. Epub 2016 Feb 27. Biochim Biophys Acta. 2016. PMID: 26923434
99 results