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A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.
Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. Huang T, et al. Among authors: james cd. Nat Commun. 2016 Oct 4;7:12885. doi: 10.1038/ncomms12885. Nat Commun. 2016. PMID: 27698350 Free PMC article.
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma.
Pelloski CE, Ballman KV, Furth AF, Zhang L, Lin E, Sulman EP, Bhat K, McDonald JM, Yung WK, Colman H, Woo SY, Heimberger AB, Suki D, Prados MD, Chang SM, Barker FG 2nd, Buckner JC, James CD, Aldape K. Pelloski CE, et al. Among authors: james cd. J Clin Oncol. 2007 Jun 1;25(16):2288-94. doi: 10.1200/JCO.2006.08.0705. J Clin Oncol. 2007. PMID: 17538175
NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification.
Yoshida Y, Ozawa T, Yao TW, Shen W, Brown D, Parsa AT, Raizer JJ, Cheng SY, Stegh AH, Mazar AP, Giles FJ, Sarkaria JN, Butowski N, Nicolaides T, James CD. Yoshida Y, et al. Among authors: james cd. Mol Cancer Ther. 2014 Dec;13(12):2919-29. doi: 10.1158/1535-7163.MCT-14-0306. Epub 2014 Oct 13. Mol Cancer Ther. 2014. PMID: 25313012 Free PMC article.
Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.
Feng H, Li Y, Yin Y, Zhang W, Hou Y, Zhang L, Li Z, Xie B, Gao WQ, Sarkaria JN, Raizer JJ, James CD, Parsa AT, Hu B, Cheng SY. Feng H, et al. Among authors: james cd. Neuro Oncol. 2015 Jun;17(6):832-42. doi: 10.1093/neuonc/nou323. Epub 2014 Dec 2. Neuro Oncol. 2015. PMID: 25468898 Free PMC article.
miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma.
Kouri FM, Hurley LA, Daniel WL, Day ES, Hua Y, Hao L, Peng CY, Merkel TJ, Queisser MA, Ritner C, Zhang H, James CD, Sznajder JI, Chin L, Giljohann DA, Kessler JA, Peter ME, Mirkin CA, Stegh AH. Kouri FM, et al. Among authors: james cd. Genes Dev. 2015 Apr 1;29(7):732-45. doi: 10.1101/gad.257394.114. Genes Dev. 2015. PMID: 25838542 Free PMC article.
MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma.
Bell JB, Eckerdt FD, Alley K, Magnusson LP, Hussain H, Bi Y, Arslan AD, Clymer J, Alvarez AA, Goldman S, Cheng SY, Nakano I, Horbinski C, Davuluri RV, James CD, Platanias LC. Bell JB, et al. Among authors: james cd. Mol Cancer Res. 2016 Oct;14(10):984-993. doi: 10.1158/1541-7786.MCR-16-0172. Epub 2016 Jun 30. Mol Cancer Res. 2016. PMID: 27364770 Free PMC article.
Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.
Hashizume R, Zhang A, Mueller S, Prados MD, Lulla RR, Goldman S, Saratsis AM, Mazar AP, Stegh AH, Cheng SY, Horbinski C, Haas-Kogan DA, Sarkaria JN, Waldman T, James CD. Hashizume R, et al. Among authors: james cd. Neuro Oncol. 2016 Nov;18(11):1519-1528. doi: 10.1093/neuonc/now106. Epub 2016 Jul 1. Neuro Oncol. 2016. PMID: 27370397 Free PMC article.
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.
Piunti A, Hashizume R, Morgan MA, Bartom ET, Horbinski CM, Marshall SA, Rendleman EJ, Ma Q, Takahashi YH, Woodfin AR, Misharin AV, Abshiru NA, Lulla RR, Saratsis AM, Kelleher NL, James CD, Shilatifard A. Piunti A, et al. Among authors: james cd. Nat Med. 2017 Apr;23(4):493-500. doi: 10.1038/nm.4296. Epub 2017 Feb 27. Nat Med. 2017. PMID: 28263307 Free PMC article.
Therapeutic Hypothesis Testing With Rodent Brain Tumor Models.
Wainwright DA, Horbinski CM, Hashizume R, James CD. Wainwright DA, et al. Among authors: james cd. Neurotherapeutics. 2017 Apr;14(2):385-392. doi: 10.1007/s13311-017-0523-1. Neurotherapeutics. 2017. PMID: 28321824 Free PMC article. Review.
373 results