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Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
Villar-Piqué A, Lopes da Fonseca T, Sant'Anna R, Szegö ÉM, Fonseca-Ornelas L, Pinho R, Carija A, Gerhardt E, Masaracchia C, Abad Gonzalez E, Rossetti G, Carloni P, Fernández CO, Foguel D, Milosevic I, Zweckstetter M, Ventura S, Outeiro TF. Villar-Piqué A, et al. Among authors: zweckstetter m. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6506-E6515. doi: 10.1073/pnas.1606791113. Epub 2016 Oct 5. Proc Natl Acad Sci U S A. 2016. PMID: 27708160 Free PMC article.
Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease.
Rasia RM, Bertoncini CW, Marsh D, Hoyer W, Cherny D, Zweckstetter M, Griesinger C, Jovin TM, Fernández CO. Rasia RM, et al. Among authors: zweckstetter m. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4294-9. doi: 10.1073/pnas.0407881102. Epub 2005 Mar 14. Proc Natl Acad Sci U S A. 2005. PMID: 15767574 Free PMC article.
Charge-induced molecular alignment of intrinsically disordered proteins.
Skora L, Cho MK, Kim HY, Becker S, Fernandez CO, Blackledge M, Zweckstetter M. Skora L, et al. Among authors: zweckstetter m. Angew Chem Int Ed Engl. 2006 Oct 27;45(42):7012-5. doi: 10.1002/anie.200602317. Angew Chem Int Ed Engl. 2006. PMID: 17009286 No abstract available.
291 results