Shen HW - Search Results

1

Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice.

Jiang XL, Shen HW, Mager DE, Schmidt S, Yu AM. Jiang XL, et al. Among authors: shen hw. Acta Pharm Sin B. 2016 Sep;6(5):492-503. doi: 10.1016/j.apsb.2016.07.007. Epub 2016 Aug 6. Acta Pharm Sin B. 2016. PMID: 27709018 Free PMC article.

2

Modification of 5-methoxy-N,N-dimethyltryptamine-induced hyperactivity by monoamine oxidase A inhibitor harmaline in mice and the underlying serotonergic mechanisms.

Jiang XL, Shen HW, Yu AM. Jiang XL, et al. Among authors: shen hw. Pharmacol Rep. 2016 Jun;68(3):608-15. doi: 10.1016/j.pharep.2016.01.008. Epub 2016 Feb 5. Pharmacol Rep. 2016. PMID: 26977821 Free PMC article.

3

Pinoline may be used as a probe for CYP2D6 activity.

Jiang XL, Shen HW, Yu AM. Jiang XL, et al. Among authors: shen hw. Drug Metab Dispos. 2009 Mar;37(3):443-6. doi: 10.1124/dmd.108.025056. Epub 2008 Dec 18. Drug Metab Dispos. 2009. PMID: 19095720 Free PMC article.

4

Effects of CYP2D6 status on harmaline metabolism, pharmacokinetics and pharmacodynamics, and a pharmacogenetics-based pharmacokinetic model.

Wu C, Jiang XL, Shen HW, Yu AM. Wu C, et al. Among authors: shen hw. Biochem Pharmacol. 2009 Sep 15;78(6):617-24. doi: 10.1016/j.bcp.2009.05.011. Epub 2009 May 13. Biochem Pharmacol. 2009. PMID: 19445902 Free PMC article.

5

Difference in desipramine metabolic profile between wild-type and CYP2D6-humanized mice.

Shen HW, Yu AM. Shen HW, et al. Drug Metab Lett. 2009 Dec;3(4):234-41. doi: 10.2174/187231209790218118. Drug Metab Lett. 2009. PMID: 19995332 Free PMC article.

6

Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N,N-dimethyltryptamine metabolism and pharmacokinetics.

Shen HW, Wu C, Jiang XL, Yu AM. Shen HW, et al. Biochem Pharmacol. 2010 Jul 1;80(1):122-8. doi: 10.1016/j.bcp.2010.02.020. Epub 2010 Mar 3. Biochem Pharmacol. 2010. PMID: 20206139 Free PMC article.

7

Development of a LC-MS/MS method to analyze 5-methoxy-N,N-dimethyltryptamine and bufotenine, and application to pharmacokinetic study.

Shen HW, Jiang XL, Yu AM. Shen HW, et al. Bioanalysis. 2009 Apr;1(1):87-95. doi: 10.4155/bio.09.7. Bioanalysis. 2009. PMID: 20523750 Free PMC article.

8

Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions.

Shen HW, Jiang XL, Winter JC, Yu AM. Shen HW, et al. Curr Drug Metab. 2010 Oct;11(8):659-66. doi: 10.2174/138920010794233495. Curr Drug Metab. 2010. PMID: 20942780 Free PMC article. Review.

9

Nonlinear pharmacokinetics of 5-methoxy-N,N-dimethyltryptamine in mice.

Shen HW, Jiang XL, Yu AM. Shen HW, et al. Drug Metab Dispos. 2011 Jul;39(7):1227-34. doi: 10.1124/dmd.111.039107. Epub 2011 Apr 4. Drug Metab Dispos. 2011. PMID: 21464174 Free PMC article.

10

Humanized transgenic mouse models for drug metabolism and pharmacokinetic research.

Shen HW, Jiang XL, Gonzalez FJ, Yu AM. Shen HW, et al. Curr Drug Metab. 2011 Dec;12(10):997-1006. doi: 10.2174/138920011798062265. Curr Drug Metab. 2011. PMID: 22023319 Free PMC article.

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