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HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.
Ghiboub M, Zhao J, Li Yim AYF, Schilderink R, Verseijden C, van Hamersveld PHP, Duarte JM, Hakvoort TBM, Admiraal I, Harker NR, Tough DF, Henneman P, de Winther MPJ, de Jonge WJ. Ghiboub M, et al. Among authors: schilderink r. Front Immunol. 2020 Oct 5;11:550769. doi: 10.3389/fimmu.2020.550769. eCollection 2020. Front Immunol. 2020. PMID: 33123128 Free PMC article.
miR-511-3p, embedded in the macrophage mannose receptor gene, contributes to intestinal inflammation.
Heinsbroek SE, Squadrito ML, Schilderink R, Hilbers FW, Verseijden C, Hofmann M, Helmke A, Boon L, Wildenberg ME, Roelofs JJ, Ponsioen CY, Peters CP, Te Velde AA, Gordon S, De Palma M, de Jonge WJ. Heinsbroek SE, et al. Among authors: schilderink r. Mucosal Immunol. 2016 Jul;9(4):960-73. doi: 10.1038/mi.2015.113. Epub 2015 Nov 4. Mucosal Immunol. 2016. PMID: 26530135 Free article.
In Vitro Simulation of the Environment in the Upper Gastrointestinal Lumen After Drug Administration in the Fed State Using the TIM-1 System and Comparison With Luminal Data in Adults.
Pentafragka C, Tomaszewska I, Bellmann S, Minekus M, Schilderink R, Vertzoni M, McAllister M, Reppas C. Pentafragka C, et al. Among authors: schilderink r. J Pharm Sci. 2022 Jan;111(1):197-205. doi: 10.1016/j.xphs.2021.10.010. Epub 2021 Oct 19. J Pharm Sci. 2022. PMID: 34673096
On the usefulness of compendial setups and tiny-TIM system in evaluating the in vivo performance of oral drug products with various release profiles in the fasted state: Case example sodium salt of A6197.
Schilderink R, Protopappa M, Fleth-James J, Vertzoni M, Schaefer K, Havenaar R, Kulla I, Metzger M, Reppas C. Schilderink R, et al. Eur J Pharm Biopharm. 2020 Apr;149:154-162. doi: 10.1016/j.ejpb.2020.02.003. Epub 2020 Feb 11. Eur J Pharm Biopharm. 2020. PMID: 32057905 Clinical Trial.
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration.
Butler J, Hens B, Vertzoni M, Brouwers J, Berben P, Dressman J, Andreas CJ, Schaefer KJ, Mann J, McAllister M, Jamei M, Kostewicz E, Kesisoglou F, Langguth P, Minekus M, Müllertz A, Schilderink R, Koziolek M, Jedamzik P, Weitschies W, Reppas C, Augustijns P. Butler J, et al. Among authors: schilderink r. Eur J Pharm Biopharm. 2019 Mar;136:70-83. doi: 10.1016/j.ejpb.2018.12.010. Epub 2018 Dec 20. Eur J Pharm Biopharm. 2019. PMID: 30579851 Free article.
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