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Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.
Loppnow H, Zhang L, Buerke M, Lautenschläger M, Chen L, Frister A, Schlitt A, Luther T, Song N, Hofmann B, Rose-John S, Silber RE, Müller-Werdan U, Werdan K. Loppnow H, et al. Among authors: frister a. J Cell Mol Med. 2011 Apr;15(4):994-1004. doi: 10.1111/j.1582-4934.2010.01036.x. J Cell Mol Med. 2011. PMID: 20158569 Free PMC article. Clinical Trial.
Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production.
Chen L, Frister A, Wang S, Ludwig A, Behr H, Pippig S, Li B, Simm A, Hofmann B, Pilowski C, Koch S, Buerke M, Rose-John S, Werdan K, Loppnow H. Chen L, et al. Among authors: frister a. Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H987-96. doi: 10.1152/ajpheart.01158.2008. Epub 2009 Jan 23. Am J Physiol Heart Circ Physiol. 2009. PMID: 19168721 Free article.