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IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Mace TA, Shakya R, Pitarresi JR, Swanson B, McQuinn CW, Loftus S, Nordquist E, Cruz-Monserrate Z, Yu L, Young G, Zhong X, Zimmers TA, Ostrowski MC, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski GB. Mace TA, et al. Among authors: yu l. Gut. 2018 Feb;67(2):320-332. doi: 10.1136/gutjnl-2016-311585. Epub 2016 Oct 21. Gut. 2018. PMID: 27797936 Free PMC article.
Melanoma cells exhibit variable signal transducer and activator of transcription 1 phosphorylation and a reduced response to IFN-alpha compared with immune effector cells.
Lesinski GB, Trefry J, Brasdovich M, Kondadasula SV, Sackey K, Zimmerer JM, Chaudhury AR, Yu L, Zhang X, Crespin TR, Walker MJ, Carson WE 3rd. Lesinski GB, et al. Among authors: yu l. Clin Cancer Res. 2007 Sep 1;13(17):5010-9. doi: 10.1158/1078-0432.CCR-06-3092. Clin Cancer Res. 2007. PMID: 17785551
Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G, Ostrowski MC. Wallace JA, et al. Among authors: yu l. PLoS One. 2013 Aug 16;8(8):e71533. doi: 10.1371/journal.pone.0071533. eCollection 2013. PLoS One. 2013. PMID: 23977064 Free PMC article.
Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis.
Wallace JA, Pitarresi JR, Sharma N, Palettas M, Cuitiño MC, Sizemore ST, Yu L, Sanderlin A, Rosol TJ, Mehta KD, Sizemore GM, Ostrowski MC. Wallace JA, et al. Among authors: yu l. Front Oncol. 2014 Apr 23;4:87. doi: 10.3389/fonc.2014.00087. eCollection 2014. Front Oncol. 2014. PMID: 24795864 Free PMC article.
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G. Caserta E, et al. Among authors: yu l. Genes Dev. 2015 Aug 15;29(16):1707-20. doi: 10.1101/gad.262568.115. Genes Dev. 2015. PMID: 26302789 Free PMC article.
Myeloid-Derived Suppressor Cells Express Bruton's Tyrosine Kinase and Can Be Depleted in Tumor-Bearing Hosts by Ibrutinib Treatment.
Stiff A, Trikha P, Wesolowski R, Kendra K, Hsu V, Uppati S, McMichael E, Duggan M, Campbell A, Keller K, Landi I, Zhong Y, Dubovsky J, Howard JH, Yu L, Harrington B, Old M, Reiff S, Mace T, Tridandapani S, Muthusamy N, Caligiuri MA, Byrd JC, Carson WE 3rd. Stiff A, et al. Among authors: yu l. Cancer Res. 2016 Apr 15;76(8):2125-36. doi: 10.1158/0008-5472.CAN-15-1490. Epub 2016 Feb 15. Cancer Res. 2016. PMID: 26880800 Free PMC article.
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC. Liu X, et al. Among authors: yu l. Genes Dev. 2016 Sep 1;30(17):1943-55. doi: 10.1101/gad.283499.116. Epub 2016 Sep 15. Genes Dev. 2016. PMID: 27633013 Free PMC article.
Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, Rosol TJ, Shakya R, Ludwig T, Lesinski GB, Fernandez SA, Konieczny SF, Leone G, Wu J, Ostrowski MC. Pitarresi JR, et al. Among authors: yu l. Neoplasia. 2016 Sep;18(9):541-52. doi: 10.1016/j.neo.2016.07.006. Neoplasia. 2016. PMID: 27659014 Free PMC article.
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