A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder.
Galaj E, Bi GH, Klein B, Hempel B, Shaik AB, Gogarnoiu ES, Friedman J, Lam J, Rais R, Reed JF, Bloom SH, Swanson TL, Schmachtenberg JL, Eshleman AJ, Janowsky A, Xi ZX, Newman AH.
Galaj E, et al. Among authors: reed jf.
Neuropsychopharmacology. 2022 Dec;47(13):2309-2318. doi: 10.1038/s41386-022-01379-1. Epub 2022 Jul 25.
Neuropsychopharmacology. 2022.
PMID: 35879349
Free PMC article.