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305 results

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Page 1
Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.
Mathew G, Hannan A, Hertzler-Schaefer K, Wang F, Feng GS, Zhong J, Zhao JJ, Downward J, Zhang X. Mathew G, et al. Among authors: downward j. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13156-13161. doi: 10.1073/pnas.1604450113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799550 Free PMC article.
P110delta, a novel phosphoinositide 3-kinase in leukocytes.
Vanhaesebroeck B, Welham MJ, Kotani K, Stein R, Warne PH, Zvelebil MJ, Higashi K, Volinia S, Downward J, Waterfield MD. Vanhaesebroeck B, et al. Among authors: downward j. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4330-5. doi: 10.1073/pnas.94.9.4330. Proc Natl Acad Sci U S A. 1997. PMID: 9113989 Free PMC article.
SnapShot: Ras Signaling.
Cully M, Downward J. Cully M, et al. Among authors: downward j. Cell. 2008 Jun 27;133(7):1292-1292.e1. doi: 10.1016/j.cell.2008.06.020. Cell. 2008. PMID: 18585361 Free article. No abstract available.
Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors.
Tsolakos N, Durrant TN, Chessa T, Suire SM, Oxley D, Kulkarni S, Downward J, Perisic O, Williams RL, Stephens L, Hawkins PT. Tsolakos N, et al. Among authors: downward j. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12176-12181. doi: 10.1073/pnas.1803446115. Epub 2018 Nov 15. Proc Natl Acad Sci U S A. 2018. PMID: 30442661 Free PMC article.
The activation of phosphatidylinositol 3-kinase by Ras.
Kodaki T, Woscholski R, Hallberg B, Rodriguez-Viciana P, Downward J, Parker PJ. Kodaki T, et al. Among authors: downward j. Curr Biol. 1994 Sep 1;4(9):798-806. doi: 10.1016/s0960-9822(00)00177-9. Curr Biol. 1994. PMID: 7820549
Phosphatidylinositol 3' kinase: one of the effectors of Ras.
Rodriguez-Viciana P, Marte BM, Warne PH, Downward J. Rodriguez-Viciana P, et al. Among authors: downward j. Philos Trans R Soc Lond B Biol Sci. 1996 Feb 29;351(1336):225-31; discussion 231-2. doi: 10.1098/rstb.1996.0020. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8650270 Review.
Ras signalling and apoptosis.
Downward J. Downward J. Curr Opin Genet Dev. 1998 Feb;8(1):49-54. doi: 10.1016/s0959-437x(98)80061-0. Curr Opin Genet Dev. 1998. PMID: 9529605 Review.
305 results