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Page 1
Single ocular injection of a sustained-release anti-VEGF delivers 6months pharmacokinetics and efficacy in a primate laser CNV model.
Adamson P, Wilde T, Dobrzynski E, Sychterz C, Polsky R, Kurali E, Haworth R, Tang CM, Korczynska J, Cook F, Papanicolaou I, Tsikna L, Roberts C, Hughes-Thomas Z, Walford J, Gibson D, Warrack J, Smal J, Verrijk R, Miller PE, Nork TM, Prusakiewicz J, Streit T, Sorden S, Struble C, Christian B, Catchpole IR. Adamson P, et al. Among authors: korczynska j. J Control Release. 2016 Dec 28;244(Pt A):1-13. doi: 10.1016/j.jconrel.2016.10.026. Epub 2016 Nov 1. J Control Release. 2016. PMID: 27810558 Free PMC article.
Novel Interaction Mechanism of a Domain Antibody-based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency than Ranibizumab and Bevacizumab and Improved Capacity over Aflibercept.
Walker A, Chung CW, Neu M, Burman M, Batuwangala T, Jones G, Tang CM, Steward M, Mullin M, Tournier N, Lewis A, Korczynska J, Chung V, Catchpole I. Walker A, et al. Among authors: korczynska j. J Biol Chem. 2016 Mar 11;291(11):5500-5511. doi: 10.1074/jbc.M115.691162. Epub 2016 Jan 4. J Biol Chem. 2016. PMID: 26728464 Free PMC article.
Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation.
Liddle J, Hutchinson JP, Kitchen S, Rowland P, Neu M, Cecconie T, Holmes DS, Jones E, Korczynska J, Koumantou D, Lea JD, Nickels L, Pemberton M, Phillipou A, Schneck JL, Sheehan H, Tinworth CP, Uings I, Wojno-Picon J, Young RJ, Stratikos E. Liddle J, et al. Among authors: korczynska j. J Med Chem. 2020 Mar 26;63(6):3348-3358. doi: 10.1021/acs.jmedchem.9b02123. Epub 2020 Mar 9. J Med Chem. 2020. PMID: 32109056
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Wyllie S, Brand S, Thomas M, De Rycker M, Chung CW, Pena I, Bingham RP, Bueren-Calabuig JA, Cantizani J, Cebrian D, Craggs PD, Ferguson L, Goswami P, Hobrath J, Howe J, Jeacock L, Ko EJ, Korczynska J, MacLean L, Manthri S, Martinez MS, Mata-Cantero L, Moniz S, Nühs A, Osuna-Cabello M, Pinto E, Riley J, Robinson S, Rowland P, Simeons FRC, Shishikura Y, Spinks D, Stojanovski L, Thomas J, Thompson S, Viayna Gaza E, Wall RJ, Zuccotto F, Horn D, Ferguson MAJ, Fairlamb AH, Fiandor JM, Martin J, Gray DW, Miles TJ, Gilbert IH, Read KD, Marco M, Wyatt PG. Wyllie S, et al. Among authors: korczynska j. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9318-9323. doi: 10.1073/pnas.1820175116. Epub 2019 Apr 8. Proc Natl Acad Sci U S A. 2019. PMID: 30962368 Free PMC article.
Microscale vapour diffusion for protein crystallization.
Korczyńska J, Hu TC, Smith DK, Jenkins J, Lewis R, Edwards T, Brzozowski AM. Korczyńska J, et al. Acta Crystallogr D Biol Crystallogr. 2007 Sep;63(Pt 9):1009-15. doi: 10.1107/S0907444907037857. Epub 2007 Aug 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17704570
The structure of a family GH25 lysozyme from Aspergillus fumigatus.
Korczynska JE, Danielsen S, Schagerlöf U, Turkenburg JP, Davies GJ, Wilson KS, Taylor EJ. Korczynska JE, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):973-7. doi: 10.1107/S1744309110025601. Epub 2010 Aug 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823508 Free PMC article.
55 results