Yang Y - Search Results

1

A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism.

Yang Y, Davis I, Ha U, Wang Y, Shin I, Liu A. Yang Y, et al. J Biol Chem. 2016 Dec 16;291(51):26252-26261. doi: 10.1074/jbc.M116.759712. Epub 2016 Nov 3. J Biol Chem. 2016. PMID: 27810899 Free PMC article.

2

Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism.

Davis I, Yang Y, Wherritt D, Liu A. Davis I, et al. Among authors: yang y. J Biol Chem. 2018 Jun 22;293(25):9594-9603. doi: 10.1074/jbc.RA118.003320. Epub 2018 Apr 27. J Biol Chem. 2018. PMID: 29703752 Free PMC article.

3

Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities.

Yang Y, Liu F, Liu A. Yang Y, et al. J Biol Chem. 2018 Jul 6;293(27):10415-10424. doi: 10.1074/jbc.RA118.002698. Epub 2018 May 21. J Biol Chem. 2018. PMID: 29784877 Free PMC article.

4

Quaternary structure of α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase (ACMSD) controls its activity.

Yang Y, Davis I, Matsui T, Rubalcava I, Liu A. Yang Y, et al. J Biol Chem. 2019 Jul 26;294(30):11609-11621. doi: 10.1074/jbc.RA119.009035. Epub 2019 Jun 12. J Biol Chem. 2019. PMID: 31189654 Free PMC article.

5

Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.

Yang Y, Borel T, de Azambuja F, Johnson D, Sorrentino JP, Udokwu C, Davis I, Liu A, Altman RA. Yang Y, et al. J Med Chem. 2021 Jan 14;64(1):797-811. doi: 10.1021/acs.jmedchem.0c01762. Epub 2020 Dec 28. J Med Chem. 2021. PMID: 33369426 Free PMC article.

6

Substrate-Assisted Hydroxylation and O-Demethylation in the Peroxidase-like Cytochrome P450 Enzyme CYP121.

Nguyen RC, Yang Y, Wang Y, Davis I, Liu A. Nguyen RC, et al. Among authors: yang y. ACS Catal. 2020 Jan 17;10(2):1628-1639. doi: 10.1021/acscatal.9b04596. Epub 2019 Dec 20. ACS Catal. 2020. PMID: 32391185 Free PMC article.

7

Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens.

Wang Y, Liu KF, Yang Y, Davis I, Liu A. Wang Y, et al. Among authors: yang y. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):19720-19730. doi: 10.1073/pnas.2005327117. Epub 2020 Jul 30. Proc Natl Acad Sci U S A. 2020. PMID: 32732435 Free PMC article.

8

Nuclear transplantation in teleosts. Hybrid fish from the nucleus of crucian and the cytoplasm of carp.

Yan SY, Lu DY, Du M, Li GS, Lin LT, Jin GQ, Wang H, Yang YQ, Xia DQ, Liu AZ, et al. Yan SY, et al. Among authors: yang yq. Sci Sin B. 1984 Oct;27(10):1029-34. Sci Sin B. 1984. PMID: 6597566

9

Evaluations of the Perturbation Resistance of the Deep-Learning-Based Ligand Conformation Optimization Algorithm.

Xin M, Wang Z, Wang Z, Qu Y, Yang Y, Li YQ, Zhao M, Zheng L, Mu Y, Li W. Xin M, et al. Among authors: yang y. J Chem Inf Model. 2024 Dec 26. doi: 10.1021/acs.jcim.4c01096. Online ahead of print. J Chem Inf Model. 2024. PMID: 39724561

10

AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription.

Zhou L, Yang Y, Qiao Q, Mi Y, Gan Y, Zheng Y, Wang Y, Liu M, Zhou Y. Zhou L, et al. Among authors: yang y. J Cancer Res Clin Oncol. 2024 Dec 26;151(1):15. doi: 10.1007/s00432-024-06039-z. J Cancer Res Clin Oncol. 2024. PMID: 39724412

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