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Page 1
Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals.
Bellinger AM, Jafari M, Grant TM, Zhang S, Slater HC, Wenger EA, Mo S, Lee YL, Mazdiyasni H, Kogan L, Barman R, Cleveland C, Booth L, Bensel T, Minahan D, Hurowitz HM, Tai T, Daily J, Nikolic B, Wood L, Eckhoff PA, Langer R, Traverso G. Bellinger AM, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra157. doi: 10.1126/scitranslmed.aag2374. Sci Transl Med. 2016. PMID: 27856796 Free PMC article.
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy.
Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, Wu SJ, Grant T, Bellinger AM, Nikolic B, Hayward A, Wood L, Eckhoff PA, Nowak MA, Langer R, Traverso G. Kirtane AR, et al. Among authors: bellinger am. Nat Commun. 2018 Jan 9;9(1):2. doi: 10.1038/s41467-017-02294-6. Nat Commun. 2018. PMID: 29317618 Free PMC article.
A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment.
Verma M, Vishwanath K, Eweje F, Roxhed N, Grant T, Castaneda M, Steiger C, Mazdiyasni H, Bensel T, Minahan D, Soares V, Salama JAF, Lopes A, Hess K, Cleveland C, Fulop DJ, Hayward A, Collins J, Tamang SM, Hua T, Ikeanyi C, Zeidman G, Mule E, Boominathan S, Popova E, Miller JB, Bellinger AM, Collins D, Leibowitz D, Batra S, Ahuja S, Bajiya M, Batra S, Sarin R, Agarwal U, Khaparde SD, Gupta NK, Gupta D, Bhatnagar AK, Chopra KK, Sharma N, Khanna A, Chowdhury J, Stoner R, Slocum AH, Cima MJ, Furin J, Langer R, Traverso G. Verma M, et al. Among authors: bellinger am. Sci Transl Med. 2019 Mar 13;11(483):eaau6267. doi: 10.1126/scitranslmed.aau6267. Sci Transl Med. 2019. PMID: 30867322 Free PMC article.
A pharmaceutical answer to nonadherence: Once weekly oral memantine for Alzheimer's disease.
Kanasty R, Low S, Bhise N, Yang J, Peeke E, Schwarz M, Wright J, Carter B, Moorthy S, Grant T, DeBenedictis B, Bishoff M, Simses C, Bellinger AM. Kanasty R, et al. Among authors: bellinger am. J Control Release. 2019 Jun 10;303:34-41. doi: 10.1016/j.jconrel.2019.03.022. Epub 2019 Mar 27. J Control Release. 2019. PMID: 30928488 Free PMC article.
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, Wang K, Iyer S, Dutta C, Clendaniel V, Amaonye M, Beach A, Berth K, Biswas S, Braun MC, Chen HM, Colace TV, Ganey JD, Gangopadhyay SA, Garrity R, Kasiewicz LN, Lavoie J, Madsen JA, Matsumoto Y, Mazzola AM, Nasrullah YS, Nneji J, Ren H, Sanjeev A, Shay M, Stahley MR, Fan SHY, Tam YK, Gaudelli NM, Ciaramella G, Stolz LE, Malyala P, Cheng CJ, Rajeev KG, Rohde E, Bellinger AM, Kathiresan S. Musunuru K, et al. Among authors: bellinger am. Nature. 2021 May;593(7859):429-434. doi: 10.1038/s41586-021-03534-y. Epub 2021 May 19. Nature. 2021. PMID: 34012082
Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma.
O'Donnell-Luria AH, Lin AP, Merugumala SK, Rohr F, Waisbren SE, Lynch R, Tchekmedyian V, Goldberg AD, Bellinger A, McFaline-Figueroa JR, Simon T, Gershanik EF, Levy BD, Cohen DE, Samuels MA, Berry GT, Frank NY. O'Donnell-Luria AH, et al. Mol Genet Metab. 2017 May;121(1):9-15. doi: 10.1016/j.ymgme.2017.03.003. Epub 2017 Mar 10. Mol Genet Metab. 2017. PMID: 28408159
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