Lawrence D - Search Results

1

Randomized assessment of imatinib in patients with acute ischaemic stroke treated with intravenous thrombolysis.

Wahlgren N, Thorén M, Höjeberg B, Käll TB, Laska AC, Sjöstrand C, Höijer J, Almqvist H, Holmin S, Lilja A, Fredriksson L, Lawrence D, Eriksson U, Ahmed N. Wahlgren N, et al. Among authors: lawrence d. J Intern Med. 2017 Mar;281(3):273-283. doi: 10.1111/joim.12576. Epub 2016 Nov 14. J Intern Med. 2017. PMID: 27862464 Free PMC article. Clinical Trial.

2

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.

Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J, Gao Y, Pietras K, Mann K, Yepes M, Strickland DK, Betsholtz C, Eriksson U, Lawrence DA. Su EJ, et al. Nat Med. 2008 Jul;14(7):731-7. doi: 10.1038/nm1787. Epub 2008 Jun 22. Nat Med. 2008. PMID: 18568034 Free PMC article.

3

Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke.

Su EJ, Fredriksson L, Schielke GP, Eriksson U, Lawrence DA. Su EJ, et al. Among authors: lawrence da. J Thromb Haemost. 2009 Jul;7 Suppl 1(Suppl 1):155-8. doi: 10.1111/j.1538-7836.2009.03402.x. J Thromb Haemost. 2009. PMID: 19630790 Free PMC article. Review.

4

Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities.

Fredriksson L, Nilsson I, Su EJ, Andrae J, Ding H, Betsholtz C, Eriksson U, Lawrence DA. Fredriksson L, et al. Am J Pathol. 2012 Mar;180(3):1136-1144. doi: 10.1016/j.ajpath.2011.12.006. Epub 2012 Jan 9. Am J Pathol. 2012. PMID: 22230248 Free PMC article.

5

Identification of a neurovascular signaling pathway regulating seizures in mice.

Fredriksson L, Stevenson TK, Su EJ, Ragsdale M, Moore S, Craciun S, Schielke GP, Murphy GG, Lawrence DA. Fredriksson L, et al. Ann Clin Transl Neurol. 2015 Jul;2(7):722-38. doi: 10.1002/acn3.209. Epub 2015 May 1. Ann Clin Transl Neurol. 2015. PMID: 26273685 Free PMC article.

6

Imatinib treatment reduces brain injury in a murine model of traumatic brain injury.

Su EJ, Fredriksson L, Kanzawa M, Moore S, Folestad E, Stevenson TK, Nilsson I, Sashindranath M, Schielke GP, Warnock M, Ragsdale M, Mann K, Lawrence AL, Medcalf RL, Eriksson U, Murphy GG, Lawrence DA. Su EJ, et al. Front Cell Neurosci. 2015 Oct 7;9:385. doi: 10.3389/fncel.2015.00385. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26500491 Free PMC article.

7

Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration.

Lewandowski SA, Nilsson I, Fredriksson L, Lönnerberg P, Muhl L, Zeitelhofer M, Adzemovic MZ, Nichterwitz S, Lawrence DA, Hedlund E, Eriksson U. Lewandowski SA, et al. Acta Neuropathol. 2016 Mar;131(3):453-64. doi: 10.1007/s00401-015-1520-2. Epub 2015 Dec 19. Acta Neuropathol. 2016. PMID: 26687981 Free PMC article.

8

Pharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disorders.

Lewandowski SA, Fredriksson L, Lawrence DA, Eriksson U. Lewandowski SA, et al. Pharmacol Ther. 2016 Nov;167:108-119. doi: 10.1016/j.pharmthera.2016.07.016. Epub 2016 Aug 12. Pharmacol Ther. 2016. PMID: 27524729 Free PMC article. Review.

9

tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS.

Fredriksson L, Lawrence DA, Medcalf RL. Fredriksson L, et al. Semin Thromb Hemost. 2017 Mar;43(2):154-168. doi: 10.1055/s-0036-1586229. Epub 2016 Sep 27. Semin Thromb Hemost. 2017. PMID: 27677179 Free PMC article. Review.

10

Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke.

Su EJ, Cao C, Fredriksson L, Nilsson I, Stefanitsch C, Stevenson TK, Zhao J, Ragsdale M, Sun YY, Yepes M, Kuan CY, Eriksson U, Strickland DK, Lawrence DA, Zhang L. Su EJ, et al. Acta Neuropathol. 2017 Oct;134(4):585-604. doi: 10.1007/s00401-017-1749-z. Epub 2017 Jul 19. Acta Neuropathol. 2017. PMID: 28725968 Free PMC article.

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