Blackburn GM - Search Results

1

Metal Fluorides as Analogues for Studies on Phosphoryl Transfer Enzymes.

Jin Y, Richards NG, Waltho JP, Blackburn GM. Jin Y, et al. Among authors: blackburn gm. Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4110-4128. doi: 10.1002/anie.201606474. Epub 2017 Mar 21. Angew Chem Int Ed Engl. 2017. PMID: 27862756 Free article. Review.

2

Complexes formed between calmodulin and the antagonists J-8 and TFP in solution.

Craven CJ, Whitehead B, Jones SK, Thulin E, Blackburn GM, Waltho JP. Craven CJ, et al. Among authors: blackburn gm. Biochemistry. 1996 Aug 13;35(32):10287-99. doi: 10.1021/bi9605043. Biochemistry. 1996. PMID: 8756684

3

Direct screening for phosphatase activity by turnover-based capture of protein catalysts.

Betley JR, Cesaro-Tadic S, Mekhalfia A, Rickard JH, Denham H, Partridge LJ, Plückthun A, Blackburn GM. Betley JR, et al. Among authors: blackburn gm. Angew Chem Int Ed Engl. 2002 Mar 1;41(5):775-7. doi: 10.1002/1521-3773(20020301)41:5<775::aid-anie775>3.0.co;2-f. Angew Chem Int Ed Engl. 2002. PMID: 12491332 No abstract available.

4

A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site.

Baxter NJ, Olguin LF, Golicnik M, Feng G, Hounslow AM, Bermel W, Blackburn GM, Hollfelder F, Waltho JP, Williams NH. Baxter NJ, et al. Among authors: blackburn gm. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14732-7. doi: 10.1073/pnas.0604448103. Epub 2006 Sep 21. Proc Natl Acad Sci U S A. 2006. PMID: 16990434 Free PMC article.

5

Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

Baxter NJ, Blackburn GM, Marston JP, Hounslow AM, Cliff MJ, Bermel W, Williams NH, Hollfelder F, Wemmer DE, Waltho JP. Baxter NJ, et al. Among authors: blackburn gm. J Am Chem Soc. 2008 Mar 26;130(12):3952-8. doi: 10.1021/ja078000n. Epub 2008 Mar 5. J Am Chem Soc. 2008. PMID: 18318536

6

MgF(3)(-) and alpha-galactose 1-phosphate in the active site of beta-phosphoglucomutase form a transition state analogue of phosphoryl transfer.

Baxter NJ, Hounslow AM, Bowler MW, Williams NH, Blackburn GM, Waltho JP. Baxter NJ, et al. Among authors: blackburn gm. J Am Chem Soc. 2009 Nov 18;131(45):16334-5. doi: 10.1021/ja905972m. J Am Chem Soc. 2009. PMID: 19852484

7

Structural tightening and interdomain communication in the catalytic cycle of phosphoglycerate kinase.

Marston JP, Cliff MJ, Reed MA, Blackburn GM, Hounslow AM, Craven CJ, Waltho JP. Marston JP, et al. Among authors: blackburn gm. J Mol Biol. 2010 Feb 19;396(2):345-60. doi: 10.1016/j.jmb.2009.11.052. Epub 2009 Nov 26. J Mol Biol. 2010. PMID: 19944703

8

Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.

Baxter NJ, Bowler MW, Alizadeh T, Cliff MJ, Hounslow AM, Wu B, Berkowitz DB, Williams NH, Blackburn GM, Waltho JP. Baxter NJ, et al. Among authors: blackburn gm. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4555-60. doi: 10.1073/pnas.0910333106. Epub 2010 Feb 17. Proc Natl Acad Sci U S A. 2010. PMID: 20164409 Free PMC article.

9

Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.

Cliff MJ, Bowler MW, Varga A, Marston JP, Szabó J, Hounslow AM, Baxter NJ, Blackburn GM, Vas M, Waltho JP. Cliff MJ, et al. Among authors: blackburn gm. J Am Chem Soc. 2010 May 12;132(18):6507-16. doi: 10.1021/ja100974t. J Am Chem Soc. 2010. PMID: 20397725

10

Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.

Xiaoxia L, Marston JP, Baxter NJ, Hounslow AM, Yufen Z, Blackburn GM, Cliff MJ, Waltho JP. Xiaoxia L, et al. Among authors: blackburn gm. J Am Chem Soc. 2011 Mar 23;133(11):3989-94. doi: 10.1021/ja1090035. Epub 2011 Feb 24. J Am Chem Soc. 2011. PMID: 21348513

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