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Page 1
Monoubiquitination Inhibits the Actin Bundling Activity of Fascin.
Lin S, Lu S, Mulaj M, Fang B, Keeley T, Wan L, Hao J, Muschol M, Sun J, Yang S. Lin S, et al. Among authors: wan l. J Biol Chem. 2016 Dec 30;291(53):27323-27333. doi: 10.1074/jbc.M116.767640. Epub 2016 Nov 22. J Biol Chem. 2016. PMID: 27879315 Free PMC article.
PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.
Hill KS, Roberts ER, Wang X, Marin E, Park TD, Son S, Ren Y, Fang B, Yoder S, Kim S, Wan L, Sarnaik AA, Koomen JM, Messina JL, Teer JK, Kim Y, Wu J, Chalfant CE, Kim M. Hill KS, et al. Among authors: wan l. Mol Cancer Res. 2019 Feb;17(2):583-593. doi: 10.1158/1541-7786.MCR-18-0777. Epub 2018 Oct 24. Mol Cancer Res. 2019. PMID: 30355677 Free PMC article.
PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas.
Ren Y, Bi C, Zhao X, Lwin T, Wang C, Yuan J, Silva AS, Shah BD, Fang B, Li T, Koomen JM, Jiang H, Chavez JC, Pham LV, Sudalagunta PR, Wan L, Wang X, Dalton WS, Moscinski LC, Shain KH, Vose J, Cleveland JL, Sotomayor EM, Fu K, Tao J. Ren Y, et al. Among authors: wan l. J Clin Invest. 2018 Dec 3;128(12):5517-5530. doi: 10.1172/JCI122533. Epub 2018 Nov 5. J Clin Invest. 2018. PMID: 30260324 Free PMC article.
ITCH as a potential therapeutic target in human cancers.
Yin Q, Wyatt CJ, Han T, Smalley KSM, Wan L. Yin Q, et al. Among authors: wan l. Semin Cancer Biol. 2020 Dec;67(Pt 2):117-130. doi: 10.1016/j.semcancer.2020.03.003. Epub 2020 Mar 10. Semin Cancer Biol. 2020. PMID: 32165318 Free PMC article. Review.
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP. Lee YR, et al. Among authors: wan l. Science. 2019 May 17;364(6441):eaau0159. doi: 10.1126/science.aau0159. Science. 2019. PMID: 31097636 Free PMC article.
The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. Wan L, et al. Cancer Discov. 2017 Apr;7(4):424-441. doi: 10.1158/2159-8290.CD-16-0647. Epub 2017 Feb 7. Cancer Discov. 2017. PMID: 28174173 Free PMC article.
4,556 results