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Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.
Asano S, Kitatani K, Taniguchi M, Hashimoto M, Zama K, Mitsutake S, Igarashi Y, Takeya H, Kigawa J, Hayashi A, Umehara H, Okazaki T. Asano S, et al. Among authors: mitsutake s. Mol Cell Biol. 2012 Aug;32(16):3242-52. doi: 10.1128/MCB.00121-12. Epub 2012 Jun 11. Mol Cell Biol. 2012. PMID: 22688512 Free PMC article.
Calmodulin is involved in the Ca2+-dependent activation of ceramide kinase as a calcium sensor.
Mitsutake S, Igarashi Y. Mitsutake S, et al. J Biol Chem. 2005 Dec 9;280(49):40436-41. doi: 10.1074/jbc.M501962200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203736 Free article.
We recently demonstrated that the activation of ceramide kinase (CERK) and the formation of its product, ceramide 1-phosphate (C1P), are necessary for the degranulation pathway in mast cells and that the kinase activity of this enzyme is completely dependent on the intracellular …
We recently demonstrated that the activation of ceramide kinase (CERK) and the formation of its product, ceramide 1-phosphate (C1P), are nec …
106 results