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Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation.
Fayed EA, El-Sebaey SA, Ebrahim MA, Abu-Elfotuh K, El-Sayed Mansour R, Mohamed EK, Hamdan AME, Al-Subaie FT, Albalawi GS, Albalawi TM, Hamdan AM, Mohammed AA, Ramsis TM. Fayed EA, et al. Eur J Med Chem. 2024 Dec 24;284:117201. doi: 10.1016/j.ejmech.2024.117201. Online ahead of print. Eur J Med Chem. 2024. PMID: 39731791 Free article.
Exploring a novel thiazole derivatives hybrid with fluorinated-indenoquinoxaline as dual inhibitors targeting VEGFR2/AKT and apoptosis inducers against hepatocellular carcinoma with docking simulation.
Abusaif MS, Ragab A, Fayed EA, Ammar YA, Gowifel AMH, Hassanin SO, Ahmed GE, Gohar NA. Abusaif MS, et al. Among authors: fayed ea. Bioorg Chem. 2024 Dec 2;154:108023. doi: 10.1016/j.bioorg.2024.108023. Online ahead of print. Bioorg Chem. 2024. PMID: 39644617
42 results