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The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, Baliga NS, Smith LM, Broman KW, Yandell BS, Kendziorski C, Attie AD. Keller MP, et al. Among authors: klein ma. PLoS Genet. 2016 Dec 9;12(12):e1006466. doi: 10.1371/journal.pgen.1006466. eCollection 2016 Dec. PLoS Genet. 2016. PMID: 27935966 Free PMC article.
Sirt6 regulates lifespan in Drosophila melanogaster.
Taylor JR, Wood JG, Mizerak E, Hinthorn S, Liu J, Finn M, Gordon S, Zingas L, Chang C, Klein MA, Denu JM, Gorbunova V, Seluanov A, Boeke JD, Sedivy JM, Helfand SL. Taylor JR, et al. Among authors: klein ma. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2111176119. doi: 10.1073/pnas.2111176119. Proc Natl Acad Sci U S A. 2022. PMID: 35091469 Free PMC article.
An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality.
Ferrer CM, Alders M, Postma AV, Park S, Klein MA, Cetinbas M, Pajkrt E, Glas A, van Koningsbruggen S, Christoffels VM, Mannens MMAM, Knegt L, Etchegaray JP, Sadreyev RI, Denu JM, Mostoslavsky G, van Maarle MC, Mostoslavsky R. Ferrer CM, et al. Among authors: klein ma. Genes Dev. 2018 Mar 1;32(5-6):373-388. doi: 10.1101/gad.307330.117. Epub 2018 Mar 19. Genes Dev. 2018. PMID: 29555651 Free PMC article.
Mechanism of activation for the sirtuin 6 protein deacylase.
Klein MA, Liu C, Kuznetsov VI, Feltenberger JB, Tang W, Denu JM. Klein MA, et al. J Biol Chem. 2020 Jan 31;295(5):1385-1399. doi: 10.1074/jbc.RA119.011285. Epub 2019 Dec 10. J Biol Chem. 2020. PMID: 31822559 Free PMC article.
Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health.
Trembley JH, Barach P, Tomáška JM, Poole JT, Ginex PK, Miller RF, Lindheimer JB, Szema AM, Gandy K, Siddharthan T, Kirkness JP, Nixon JP, Torres RL, Klein MA, Nurkiewicz TR, Butterick TA. Trembley JH, et al. Among authors: klein ma. Part Fibre Toxicol. 2024 Oct 21;21(1):43. doi: 10.1186/s12989-024-00606-5. Part Fibre Toxicol. 2024. PMID: 39434148 Free PMC article. Review.
152 results