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The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
Lemonnier F, Cairns RA, Inoue S, Li WY, Dupuy A, Broutin S, Martin N, Fataccioli V, Pelletier R, Wakeham A, Snow BE, de Leval L, Pujals A, Haioun C, Paci A, Tobin ER, Narayanaswamy R, Yen K, Jin S, Gaulard P, Mak TW. Lemonnier F, et al. Among authors: snow be. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15084-15089. doi: 10.1073/pnas.1617929114. Epub 2016 Dec 12. Proc Natl Acad Sci U S A. 2016. PMID: 27956631 Free PMC article.
Regulation of T cell activation, anxiety, and male aggression by RGS2.
Oliveira-Dos-Santos AJ, Matsumoto G, Snow BE, Bai D, Houston FP, Whishaw IQ, Mariathasan S, Sasaki T, Wakeham A, Ohashi PS, Roder JC, Barnes CA, Siderovski DP, Penninger JM. Oliveira-Dos-Santos AJ, et al. Among authors: snow be. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12272-7. doi: 10.1073/pnas.220414397. Proc Natl Acad Sci U S A. 2000. PMID: 11027316 Free PMC article.
Regulation of PTEN transcription by p53.
Stambolic V, MacPherson D, Sas D, Lin Y, Snow B, Jang Y, Benchimol S, Mak TW. Stambolic V, et al. Mol Cell. 2001 Aug;8(2):317-25. doi: 10.1016/s1097-2765(01)00323-9. Mol Cell. 2001. PMID: 11545734 Free article.
Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila.
Peters M, DeLuca C, Hirao A, Stambolic V, Potter J, Zhou L, Liepa J, Snow B, Arya S, Wong J, Bouchard D, Binari R, Manoukian AS, Mak TW. Peters M, et al. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11305-10. doi: 10.1073/pnas.172382899. Epub 2002 Aug 9. Proc Natl Acad Sci U S A. 2002. PMID: 12172011 Free PMC article.
DJ-1, a novel regulator of the tumor suppressor PTEN.
Kim RH, Peters M, Jang Y, Shi W, Pintilie M, Fletcher GC, DeLuca C, Liepa J, Zhou L, Snow B, Binari RC, Manoukian AS, Bray MR, Liu FF, Tsao MS, Mak TW. Kim RH, et al. Cancer Cell. 2005 Mar;7(3):263-73. doi: 10.1016/j.ccr.2005.02.010. Cancer Cell. 2005. PMID: 15766664 Free article.
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Inoue S, Hao Z, Elia AJ, Cescon D, Zhou L, Silvester J, Snow B, Harris IS, Sasaki M, Li WY, Itsumi M, Yamamoto K, Ueda T, Dominguez-Brauer C, Gorrini C, Chio II, Haight J, You-Ten A, McCracken S, Wakeham A, Ghazarian D, Penn LJ, Melino G, Mak TW. Inoue S, et al. Genes Dev. 2013 May 15;27(10):1101-14. doi: 10.1101/gad.214577.113. Genes Dev. 2013. PMID: 23699408 Free PMC article.
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